Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with all data for entry = 50012790
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Pfizer Global R&D

Curated by ChEMBL
LigandPNGBDBM50122777(1-Phenyl-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azu...)copy SMILEScopy InChI
Affinity DataKi:  4.10nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Pfizer Global R&D

Curated by ChEMBL
LigandPNGBDBM50122775(1-(4-Hydroxymethyl-phenyl)-8,9-dihydro-7H-2,7,9a-t...)copy SMILEScopy InChI
Affinity DataKi:  4.20nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Pfizer Global R&D

Curated by ChEMBL
LigandPNGBDBM50122781(1-Naphthalen-1-yl-8,9-dihydro-7H-2,7,9a-triaza-ben...)copy SMILEScopy InChI
Affinity DataKi:  4.90nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Pfizer Global R&D

Curated by ChEMBL
LigandPNGBDBM50122779(1-(4-Chloro-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-b...)copy SMILEScopy InChI
Affinity DataKi:  5.70nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Pfizer Global R&D

Curated by ChEMBL
LigandPNGBDBM50122776(1-(4-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,...)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Pfizer Global R&D

Curated by ChEMBL
LigandPNGBDBM50122772(1-(3-Dimethylaminomethyl-phenyl)-8,9-dihydro-7H-2,...)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Pfizer Global R&D

Curated by ChEMBL
LigandPNGBDBM50122774(1-(2-Chloro-phenyl)-8,9-dihydro-7H-2,7,9a-triaza-b...)copy SMILEScopy InChI
Affinity DataKi:  7.70nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Pfizer Global R&D

Curated by ChEMBL
LigandPNGBDBM50122780(1-(3-Hydroxymethyl-phenyl)-8,9-dihydro-7H-2,7,9a-t...)copy SMILEScopy InChI
Affinity DataKi:  8.80nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Pfizer Global R&D

Curated by ChEMBL
LigandPNGBDBM50122773(1-(3-Trifluoromethyl-phenyl)-8,9-dihydro-7H-2,7,9a...)copy SMILEScopy InChI
Affinity DataKi:  11.2nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Pfizer Global R&D

Curated by ChEMBL
LigandPNGBDBM50122778(1-Methyl-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azu...)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Inhibitory activity of the compound against human full length Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GDBPubMed