Compile Data Set for Download or QSAR
Found 40 Enz. Inhib. hit(s) with all data for entry = 50012852
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123324(7-Methoxy-6-oxazol-5-yl-2-phenyl-1H-quinolin-4-one...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibitory activity of the compound against IMPDH II with respect to IMP and NADMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123332(7-Methoxy-2-(4-methoxy-phenyl)-6-oxazol-5-yl-1H-qu...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123335(2-(3,4-Dimethyl-phenyl)-7-methoxy-6-oxazol-5-yl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123317(7-Methoxy-6-oxazol-5-yl-2-p-tolyl-1H-quinolin-4-on...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123321(7-Methoxy-6-oxazol-5-yl-2-m-tolyl-1H-quinolin-4-on...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123333(2-(4-Bromo-phenyl)-7-methoxy-6-oxazol-5-yl-1H-quin...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123324(7-Methoxy-6-oxazol-5-yl-2-phenyl-1H-quinolin-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123320(7-Methoxy-6-oxazol-5-yl-2-thiophen-3-yl-1H-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123319(2-(3-Hydroxy-phenyl)-7-methoxy-6-oxazol-5-yl-1H-qu...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123316(2-(3-Bromo-4-methyl-phenyl)-7-methoxy-6-oxazol-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50119045(1-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-m-tolyl-urea ...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123329(2-(3-Bromo-phenyl)-7-methoxy-6-oxazol-5-yl-1H-quin...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123318(2-(2,5-Dimethyl-phenyl)-7-methoxy-6-oxazol-5-yl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123328(2-Furan-3-yl-7-methoxy-6-oxazol-5-yl-1H-quinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123326(7-Methoxy-6-oxazol-5-yl-2-thiazol-4-yl-1H-quinolin...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123327(7-Methoxy-6-oxazol-5-yl-2-pyridin-2-yl-1H-quinolin...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123334(2-(4-Hydroxy-phenyl)-7-methoxy-6-oxazol-5-yl-1H-qu...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123331(7-Methoxy-6-oxazol-5-yl-2-pyridin-4-yl-1H-quinolin...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123317(7-Methoxy-6-oxazol-5-yl-2-p-tolyl-1H-quinolin-4-on...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMedDrugBank
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50119045(1-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-m-tolyl-urea ...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123320(7-Methoxy-6-oxazol-5-yl-2-thiophen-3-yl-1H-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123340(7-Methoxy-6-oxazol-5-yl-2-thiophen-2-yl-1H-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123342(7-Methoxy-3-methyl-6-oxazol-5-yl-2-phenyl-1H-quino...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123323(7-Methoxy-6-oxazol-5-yl-2-o-tolyl-1H-quinolin-4-on...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123338(7-Methoxy-6-oxazol-5-yl-2-pyridin-3-yl-1H-quinolin...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123335(2-(3,4-Dimethyl-phenyl)-7-methoxy-6-oxazol-5-yl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123332(7-Methoxy-2-(4-methoxy-phenyl)-6-oxazol-5-yl-1H-qu...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123324(7-Methoxy-6-oxazol-5-yl-2-phenyl-1H-quinolin-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123336(7-Methoxy-2-methyl-6-oxazol-5-yl-1H-quinolin-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123321(7-Methoxy-6-oxazol-5-yl-2-m-tolyl-1H-quinolin-4-on...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory activity of the compound against inosine monophosphate dehydrogenase IMPDH type IMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123322(2-(3-Methanesulfonyl-phenyl)-7-methoxy-6-oxazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123339(3-(7-Methoxy-6-oxazol-5-yl-4-oxo-1,4-dihydro-quino...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123337(2-Benzyl-7-methoxy-6-oxazol-5-yl-1H-quinolin-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123330(2-Dimethylamino-7-methoxy-6-oxazol-5-yl-1H-quinoli...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123343(7-Methoxy-2-methylamino-6-oxazol-5-yl-1H-quinolin-...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123325(7-Methoxy-6-oxazol-5-yl-1H-quinolin-4-one | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123341(4-(7-Methoxy-6-oxazol-5-yl-4-oxo-1,4-dihydro-quino...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Bristol-Myers Squibb PRI

Curated by ChEMBL
LigandPNGBDBM50123344(2-tert-Butyl-7-methoxy-6-oxazol-5-yl-1H-quinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human inosine monophosphate dehydrogenase IMPDH IIMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1JZTPubMed