Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with all data for entry = 50012965
Target5'-nucleotidase(Homo sapiens (Human))TBA
LigandPNGBDBM50527135(CHEMBL4452072)copy SMILEScopy InChI
Affinity DataKi:  0.381nMAssay Description:Inhibition of recombinant human C-terminal His-tagged CD73 (27 to 549 residues) expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50527135(CHEMBL4452072)copy SMILEScopy InChI
Affinity DataKi:  0.746nMAssay Description:Inhibition of recombinant rat CD73 expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for 25 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Homo sapiens (Human))TBA
LigandPNGBDBM50561892(CHEMBL4795486)copy SMILES
Affinity DataKi:  3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged CD73 (27 to 549 residues) expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TTMPubMed
Target5'-nucleotidase(Homo sapiens (Human))TBA
LigandPNGBDBM50561892(CHEMBL4795486)copy SMILES
Affinity DataKi:  4.60nMAssay Description:Inhibition of CD73 in human MDA-MB-231 cells using [2,8-3H]-AMP as substrate incubated for 25 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TTMPubMed
Target5'-nucleotidase(Homo sapiens (Human))TBA
LigandPNGBDBM50561893(CHEMBL4761798)copy SMILES
Affinity DataKi:  13nMAssay Description:Inhibition of recombinant human C-terminal His-tagged CD73 (27 to 549 residues) expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TTMPubMed
Target5'-nucleotidase(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50561892(CHEMBL4795486)copy SMILES
Affinity DataKi:  26nMAssay Description:Inhibition of recombinant rat CD73 expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for 25 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9TTMPubMed