Compile Data Set for Download or QSAR
Found 67 Enz. Inhib. hit(s) with all data for entry = 50013714
LigandPNGBDBM50568933(CHEMBL4847211)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM4077(2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568927(CHEMBL4853179)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568934(CHEMBL4864576)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568929(CHEMBL4870434)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568933(CHEMBL4847211)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568936(CHEMBL4864600)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50568932(CHEMBL4858463)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568937(CHEMBL4861488)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568932(CHEMBL4858463)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50568933(CHEMBL4847211)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM4067(2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-meth...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568950(CHEMBL4861447)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568928(CHEMBL4852860)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568931(CHEMBL4859716)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM3096(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. | 6...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM4067(2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-meth...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568935(CHEMBL4868894)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568949(CHEMBL4875011)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568943(CHEMBL4864714)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM4077(2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568939(CHEMBL4849134)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568938(CHEMBL4867467)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568927(CHEMBL4853179)copy SMILES
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568947(CHEMBL4867716)copy SMILES
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50568930(CHEMBL4871544)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50568931(CHEMBL4859716)copy SMILES
Affinity DataIC50: 18nMAssay Description:Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568937(CHEMBL4861488)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM3096(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. | 6...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568941(CHEMBL4852513)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568932(CHEMBL4858463)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568942(CHEMBL4874031)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568936(CHEMBL4864600)copy SMILES
Affinity DataIC50: 22nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568948(CHEMBL4853711)copy SMILES
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568934(CHEMBL4864576)copy SMILES
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568929(CHEMBL4870434)copy SMILES
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568945(CHEMBL4859351)copy SMILES
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568946(CHEMBL4847571)copy SMILES
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM3096(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. | 6...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50568929(CHEMBL4870434)copy SMILES
Affinity DataIC50: 59nMAssay Description:Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50568927(CHEMBL4853179)copy SMILES
Affinity DataIC50: 62nMAssay Description:Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568944(CHEMBL4856366)copy SMILES
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50568934(CHEMBL4864576)copy SMILES
Affinity DataIC50: 92nMAssay Description:Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568942(CHEMBL4874031)copy SMILES
Affinity DataIC50: 94nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568940(CHEMBL4854929)copy SMILES
Affinity DataIC50: 105nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568931(CHEMBL4859716)copy SMILES
Affinity DataIC50: 128nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568935(CHEMBL4868894)copy SMILES
Affinity DataIC50: 136nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
TargetActivin receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50568935(CHEMBL4868894)copy SMILES
Affinity DataIC50: 136nMAssay Description:Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence of [gamma33P]ATP by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568939(CHEMBL4849134)copy SMILES
Affinity DataIC50: 160nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568947(CHEMBL4867716)copy SMILES
Affinity DataIC50: 218nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
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