Compile Data Set for Download or QSAR
Found 25 Enz. Inhib. hit(s) with all data for entry = 50013955
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50571189(CHEMBL4856400)copy SMILES
Affinity DataKi:  23nMAssay Description:Non competitive type inhibition of human AChE assessed as inhibition constant using varying levels of acetylthiocholine as substrate by double recipr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by DTNB-reagent based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50523387(CHEMBL4556281)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by DTNB-reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50523387(CHEMBL4556281)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50571190(CHEMBL4878434)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by DTNB-reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50571189(CHEMBL4856400)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by DTNB-reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM8987(6-chloro-1,2,3,4-tetrahydroacridin-9-amine | 6-chl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by DTNB-reagent based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50571188(CHEMBL4874244)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by DTNB-reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50571189(CHEMBL4856400)copy SMILES
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50571188(CHEMBL4874244)copy SMILES
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50571190(CHEMBL4878434)copy SMILES
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by DTNB-reagent based Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)copy SMILEScopy InChI
Affinity DataIC50: 358nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM8987(6-chloro-1,2,3,4-tetrahydroacridin-9-amine | 6-chl...)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50571191(CHEMBL4850590)copy SMILES
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by DTNB-reagent based Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50571191(CHEMBL4850590)copy SMILES
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by DTNB-reagent based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)copy SMILEScopy InChI
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))TBA
LigandPNGBDBM50571189(CHEMBL4856400)copy SMILES
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of recombinant human nNOSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))TBA
LigandPNGBDBM50571188(CHEMBL4874244)copy SMILES
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant human nNOSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))TBA
LigandPNGBDBM50523387(CHEMBL4556281)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant human nNOSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))TBA
LigandPNGBDBM50571191(CHEMBL4850590)copy SMILES
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human nNOSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))TBA
LigandPNGBDBM10592(7-chloro-15-methyl-10-azatetracyclo[11.3.1.0^{2,11...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant human nNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))TBA
LigandPNGBDBM50571190(CHEMBL4878434)copy SMILES
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of recombinant human nNOSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44BGPubMed