Compile Data Set for Download or QSAR
Found 15 Enz. Inhib. hit(s) with all data for entry = 50014786
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))TBA
LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT8 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8HN0PubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT6 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))TBA
LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT4 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8HN0PubMed
LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT3 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8HN0PubMed
LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT1 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8HN0PubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50194756(CHEMBL3961701)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of PRMT6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8HN0PubMed
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))TBA
LigandPNGBDBM50194756(CHEMBL3961701)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of PRMT4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8HN0PubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50580050(CHEMBL5075218)copy SMILES
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8HN0PubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50580051(CHEMBL5070897)copy SMILES
Affinity DataIC50: 77nMAssay Description:Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50580053(CHEMBL5094315)copy SMILES
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8HN0PubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50580052(CHEMBL5085334)copy SMILES
Affinity DataIC50: 214nMAssay Description:Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50580054(CHEMBL5084397)copy SMILES
Affinity DataIC50: 388nMAssay Description:Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50580051(CHEMBL5070897)copy SMILES
Affinity DataIC50: 600nMAssay Description:Inhibition of FLAG-tagged PRMT6 (unknown origin) expressed in HEK293T assessed as reduction in H4R3me2a level measured after 20 hrs by SDS gel electr...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50580055(CHEMBL5089738)copy SMILES
Affinity DataIC50: 755nMAssay Description:Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))TBA
LigandPNGBDBM50580051(CHEMBL5070897)copy SMILES
Affinity DataIC50: 900nMAssay Description:Inhibition of FLAG-tagged PRMT6 (unknown origin) expressed in HEK293T assessed as reduction in H3R2me2a level measured after 20 hrs by SDS gel electr...More data for this Ligand-Target Pair