Compile Data Set for Download or QSAR
Found 22 Enz. Inhib. hit(s) with all data for entry = 50015364
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50073179(8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-be...)copy SMILEScopy InChI
Affinity DataKi:  0.970nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMedDrugBank
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155335(1-{4-[4-(3-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155341(1-(4-{4-[3-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM22890(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMedDrugBank
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155337(1-(4-{4-[2-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155336(1-{4-[4-(4-{4-[bis(4-fluorophenyl)methyl]piperazin...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155338(1-{4-[4-(4-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155334(1-(4-{4-[4-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155339(1-{4-[4-(3-{4-[bis(4-fluorophenyl)methyl]piperazin...)copy SMILEScopy InChI
Affinity DataKi:  109nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155340(1-{4-[4-(2-{4-[bis(4-fluorophenyl)methyl]piperazin...)copy SMILEScopy InChI
Affinity DataKi:  295nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155333(1-{4-[4-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)copy SMILEScopy InChI
Affinity DataKi:  305nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM22876(CHEMBL998 | Claritin | Loratadine | Sch 29851 | US...)copy SMILEScopy InChI
Affinity DataKi:  414nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMedDrugBank
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155340(1-{4-[4-(2-{4-[bis(4-fluorophenyl)methyl]piperazin...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155334(1-(4-{4-[4-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155338(1-{4-[4-(4-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155336(1-{4-[4-(4-{4-[bis(4-fluorophenyl)methyl]piperazin...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155339(1-{4-[4-(3-{4-[bis(4-fluorophenyl)methyl]piperazin...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155335(1-{4-[4-(3-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155337(1-(4-{4-[2-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155341(1-(4-{4-[3-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)copy SMILEScopy InChI
Affinity DataIC50: 194nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155333(1-{4-[4-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)copy SMILEScopy InChI
Affinity DataIC50: 213nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)copy SMILEScopy InChI
Affinity DataIC50: 873nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9VRHPubMedDrugBank