Compile Data Set for Download or QSAR
Found 45 Enz. Inhib. hit(s) with all data for entry = 50015423
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50507492(Loxo-195 | Selitrectinib | US10966985, Compound 33...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of wildtype human TRKA using poly (Glu,Tyr) 4:1 as substrate in presence of [gamma-33P]ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM374727((7S,13R)-11-fluoro-7,13-dimethyl-6,7,13,14- tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Inhibition of wildtype human TRKA using poly (Glu,Tyr) 4:1 as substrate in presence of [gamma-33P]ATP by hotspot kinase assayMore data for this Ligand-Target Pair
TargetNT-3 growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50579500(CHEMBL4864729)copy SMILES
Affinity DataIC50: 0.210nMAssay Description:Inhibition of TRKC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50579500(CHEMBL4864729)copy SMILES
Affinity DataIC50: 1.80nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586463(CHEMBL5083023)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of wildtype human TRKA using poly (Glu,Tyr) 4:1 as substrate in presence of [gamma-33P]ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50577766(CHEMBL4856292)copy SMILES
Affinity DataIC50: 3.90nMAssay Description:Inhibition of wildtype human TRKA using poly (Glu,Tyr) 4:1 as substrate in presence of [gamma-33P]ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50579500(CHEMBL4864729)copy SMILES
Affinity DataIC50: 5.60nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586469(CHEMBL5081247)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586457(CHEMBL5081608)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586462(CHEMBL5093039)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586456(CHEMBL5083720)copy SMILES
Affinity DataIC50: 8.40nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586455(CHEMBL5073918)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586454(CHEMBL5090070)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase B(Homo sapiens (Human))TBA
LigandPNGBDBM50579500(CHEMBL4864729)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant full length His-tagged human AURB expressed in baculovirus expression system using tetra-LLRASLG peptide as substrate incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586474(CHEMBL5089809)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of wildtype human TRKA using poly (Glu,Tyr) 4:1 as substrate in presence of [gamma-33P]ATP by hotspot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586474(CHEMBL5089809)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586459(CHEMBL5080510)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586473(CHEMBL5079032)copy SMILES
Affinity DataIC50: 23nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586470(CHEMBL5082243)copy SMILES
Affinity DataIC50: 27nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586460(CHEMBL5089615)copy SMILES
Affinity DataIC50: 27nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586468(CHEMBL5085280)copy SMILES
Affinity DataIC50: 29nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50579500(CHEMBL4864729)copy SMILES
Affinity DataIC50: 37nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586471(CHEMBL5092254)copy SMILES
Affinity DataIC50: 44nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586461(CHEMBL5087090)copy SMILES
Affinity DataIC50: 59nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586470(CHEMBL5082243)copy SMILES
Affinity DataIC50: 63nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586466(CHEMBL5075551)copy SMILES
Affinity DataIC50: 66nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of wildtype human TRKA using poly (Glu,Tyr) 4:1 as substrate in presence of [gamma-33P]ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586460(CHEMBL5089615)copy SMILES
Affinity DataIC50: 91nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586467(CHEMBL5076428)copy SMILES
Affinity DataIC50: 108nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586458(CHEMBL5088888)copy SMILES
Affinity DataIC50: 140nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586465(CHEMBL5077640)copy SMILES
Affinity DataIC50: 156nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586464(CHEMBL5070298)copy SMILES
Affinity DataIC50: 338nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586472(CHEMBL5090252)copy SMILES
Affinity DataIC50: 349nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586473(CHEMBL5079032)copy SMILES
Affinity DataIC50: 352nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase A(Homo sapiens (Human))TBA
LigandPNGBDBM50586474(CHEMBL5089809)copy SMILES
Affinity DataIC50: 454nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase B(Homo sapiens (Human))TBA
LigandPNGBDBM50586473(CHEMBL5079032)copy SMILES
Affinity DataIC50: 512nMAssay Description:Inhibition of recombinant full length His-tagged human AURB expressed in baculovirus expression system using tetra-LLRASLG peptide as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetAurora kinase B(Homo sapiens (Human))TBA
LigandPNGBDBM50586474(CHEMBL5089809)copy SMILES
Affinity DataIC50: 548nMAssay Description:Inhibition of recombinant full length His-tagged human AURB expressed in baculovirus expression system using tetra-LLRASLG peptide as substrate incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586467(CHEMBL5076428)copy SMILES
Affinity DataIC50: 611nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586472(CHEMBL5090252)copy SMILES
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586471(CHEMBL5092254)copy SMILES
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586475(CHEMBL5075005)copy SMILES
Affinity DataIC50: 3.59E+3nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586469(CHEMBL5081247)copy SMILES
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586465(CHEMBL5077640)copy SMILES
Affinity DataIC50: 7.41E+3nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50586468(CHEMBL5085280)copy SMILES
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of GST-tagged TRKA (G443 to G796 residues) (unknown origin) expressed in Sf9 insect cells using poly (Glu, Tyr) 4:1 as substrate incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z323JHPubMed