Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with all data for entry = 50015434
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50074364(CHEMBL350356 | N*2*-(2-Bromo-4-isopropyl-phenyl)-N...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155982(8-(Butyl-ethyl-amino)-4-(2-chloro-4-methoxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155974(8-(Butyl-ethyl-amino)-4-(2,4-dichloro-phenyl)-6-me...)copy SMILEScopy InChI
Affinity DataIC50: 0.490nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155964(8-(Butyl-ethyl-amino)-4-(2-chloro-5-fluoro-4-metho...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155967(4-(2-Bromo-4-isopropyl-phenyl)-8-(butyl-ethyl-amin...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM20977(8-[butyl(ethyl)amino]-4-(2,6-dimethoxypyridin-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.820nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155979(8-(Butyl-ethyl-amino)-4-(2-chloro-4-isopropyl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 0.910nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM20973(8-[butyl(ethyl)amino]-4-(4-methoxy-2-methylphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.920nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155975(3-Chloro-4-(8-dipropylamino-6-methyl-2-oxo-2,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155973(4-(2-Chloro-5-fluoro-4-methoxy-phenyl)-8-(ethyl-is...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155960(3-Chloro-4-[8-(cyclobutylmethyl-propyl-amino)-6-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155959(4-[8-(Butyl-ethyl-amino)-6-methyl-2-oxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155965(4-(2-Chloro-4-isopropyl-phenyl)-8-[(2-methoxy-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155977(4-[8-(Butyl-ethyl-amino)-6-methyl-2-oxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155966(4-(2-Bromo-4-isopropyl-phenyl)-8-(ethyl-furan-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155961(8-(Butyl-ethyl-amino)-4-(6-methoxy-2-methyl-pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155981(4-(2-Bromo-phenyl)-8-(butyl-ethyl-amino)-6-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155969(2-[8-(Butyl-ethyl-amino)-6-methyl-2-oxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155963(8-[Bis-(2-methoxy-ethyl)-amino]-4-(2-chloro-4-isop...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155972(8-(Butyl-ethyl-amino)-4-(4-isopropyl-phenyl)-6-met...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155970(4-(2,4-Dichloro-phenyl)-8-(2-methoxy-butylamino)-6...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155962(4-{Ethyl-[4-(4-methoxy-2-methyl-phenyl)-6-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155968(4-(2-Bromo-4-isopropyl-phenyl)-6-methyl-8-morpholi...)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155971(4-(2,4-Dichloro-phenyl)-8-(1-ethyl-propylamino)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 198nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155976(4-(2-Bromo-4-isopropyl-phenyl)-8-[ethyl-(3-methane...)copy SMILEScopy InChI
Affinity DataIC50: 305nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155978(4-(2-Chloro-4-methoxy-phenyl)-8-ethylamino-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155980(8-Butylamino-4-(2-chloro-4-methoxy-phenyl)-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FT6PubMed