Compile Data Set for Download or QSAR
Found 21 Enz. Inhib. hit(s) with all data for entry = 50015772
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155336(1-{4-[4-(4-{4-[bis(4-fluorophenyl)methyl]piperazin...)copy SMILEScopy InChI
Affinity DataKi:  3.63nMAssay Description:Binding affinity for recombinant human Histamine H1 receptor expressed in CHO K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160828(CHEMBL366925 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataKi:  5.01nMAssay Description:Binding affinity for human Histamine H1 receptor in CHO K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160827(CHEMBL179590 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataKi:  5.89nMAssay Description:Binding affinity for human Histamine H1 receptor in CHO K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM22890(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)copy SMILEScopy InChI
Affinity DataKi:  5.89nMAssay Description:Binding affinity for human Histamine H1 receptor in CHO K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMedDrugBank
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160831(CHEMBL181085 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataKi:  7.59nMAssay Description:Binding affinity for human Histamine H1 receptor in CHO K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160829(CHEMBL180233 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataKi:  9.55nMAssay Description:Binding affinity for human Histamine H1 receptor in CHO K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160830(CHEMBL360666 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataKi:  17.8nMAssay Description:Binding affinity for human Histamine H1 receptor in CHO K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160827(CHEMBL179590 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibitory concentration against 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155336(1-{4-[4-(4-{4-[bis(4-fluorophenyl)methyl]piperazin...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibitory concentration against 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160828(CHEMBL366925 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration against 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160829(CHEMBL180233 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataIC50: 102nMAssay Description:Inhibitory concentration against 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160830(CHEMBL360666 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160828(CHEMBL366925 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration against human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160831(CHEMBL181085 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataIC50: 176nMAssay Description:Inhibitory concentration against 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50155336(1-{4-[4-(4-{4-[bis(4-fluorophenyl)methyl]piperazin...)copy SMILEScopy InChI
Affinity DataIC50: 193nMAssay Description:Inhibitory concentration against human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160829(CHEMBL180233 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataIC50: 335nMAssay Description:Inhibitory concentration against human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160830(CHEMBL360666 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibitory concentration against human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160827(CHEMBL179590 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataIC50: 365nMAssay Description:Inhibitory concentration against human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50160831(CHEMBL181085 | N-hydroxycarbamate derivative)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibitory concentration against human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)copy SMILEScopy InChI
Affinity DataIC50: 518nMAssay Description:Inhibitory concentration against human 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMedDrugBank
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)copy SMILEScopy InChI
Affinity DataIC50: 873nMAssay Description:Inhibitory concentration against 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN954NPubMedDrugBank