Compile Data Set for Download or QSAR
Found 84 Enz. Inhib. hit(s) with all data for entry = 50016424
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))TBA
LigandPNGBDBM412060(2-amino-6-fluoro-N-[5-fluoro-4-[4-[4-(oxetan-3-yl)...)copy SMILEScopy InChI
Affinity DataKi: <0.150nMMore data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50084621(BMN 673 | Talazoparib)copy SMILEScopy InChI
Affinity DataKi:  0.580nMMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM209932(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-...)copy SMILEScopy InChI
Affinity DataKi:  3.30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM209932(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-...)copy SMILEScopy InChI
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))TBA
LigandPNGBDBM50594892(CHEMBL5192303)copy SMILES
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))TBA
LigandPNGBDBM50594891(CHEMBL5171087)copy SMILES
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50594028(CHEMBL5176874)copy SMILES
Affinity DataIC50: 0.25nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50084621(BMN 673 | Talazoparib)copy SMILEScopy InChI
Affinity DataIC50: 0.570nMMore data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))TBA
LigandPNGBDBM245474(US9428503, 1)copy SMILEScopy InChI
Affinity DataIC50: 0.580nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50594893(CHEMBL5188771)copy SMILES
Affinity DataIC50: 0.590nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))TBA
LigandPNGBDBM413450(7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
PDB
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50520033(CHEMBL4461382)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))TBA
LigandPNGBDBM50594881(CHEMBL5178683)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))TBA
LigandPNGBDBM50594890(CHEMBL5205796)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))TBA
LigandPNGBDBM50594889(CHEMBL5175568)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))TBA
LigandPNGBDBM50594890(CHEMBL5205796)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))TBA
LigandPNGBDBM50594889(CHEMBL5175568)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))TBA
LigandPNGBDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))TBA
LigandPNGBDBM50594883(CHEMBL5183684)copy SMILES
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))TBA
LigandPNGBDBM50594879(CHEMBL5171429)copy SMILES
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50446130(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMMore data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM50594903(CHEMBL5197954)copy SMILES
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))TBA
LigandPNGBDBM50594884(CHEMBL5197528)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50316226((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetWee1-like protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM50594900(CHEMBL5186119)copy SMILES
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
LigandPNGBDBM50594872(CHEMBL5193835)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetWee1-like protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM50594902(CHEMBL5194787)copy SMILES
Affinity DataIC50: 3.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50520040(CHEMBL4438741)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50316226((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMMore data for this Ligand-Target Pair
TargetSerine-protein kinase ATM(Homo sapiens (Human))TBA
LigandPNGBDBM50594880(CHEMBL5182423)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
LigandPNGBDBM50594873(CHEMBL5171719)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))TBA
LigandPNGBDBM50594882(CHEMBL5184207)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))TBA
LigandPNGBDBM50594028(CHEMBL5176874)copy SMILES
Affinity DataIC50: 4.20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetWee1-like protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM50594901(CHEMBL5197623)copy SMILES
Affinity DataIC50: 4.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50520037(CHEMBL4470724)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetWee1-like protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM50240826(AZD-1775 | MK-1775 | US11124518, Example AZD1775 |...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50562648(CHEMBL4744783)copy SMILES
Affinity DataIC50: 6.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))TBA
LigandPNGBDBM50594893(CHEMBL5188771)copy SMILES
Affinity DataIC50: 6.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50562646(CHEMBL4758337)copy SMILES
Affinity DataIC50: 7.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))TBA
LigandPNGBDBM412060(2-amino-6-fluoro-N-[5-fluoro-4-[4-[4-(oxetan-3-yl)...)copy SMILEScopy InChI
Ligand InfoPurchaseMCE
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))TBA
LigandPNGBDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50520034(CHEMBL4541731)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
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