Compile Data Set for Download or QSAR
Found 35 Enz. Inhib. hit(s) with all data for entry = 50017259
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179795(CHEMBL382690 | PVKRRL-(3-Cl)F-NH2)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179784(CHEMBL381053 | N-((S)-1-((S)-1-(trans-2-(3-chlorop...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179803(CHEMBL440581 | PVKRRLFA)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179797(CHEMBL206400 | PAKRRLFG)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179798(CHEMBL206617 | PVKRRLFG)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179789(CHEMBL381309 | PVKRRLF)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179801(AVKRRLFG | CHEMBL381957)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179814(CHEMBL205076 | N-((S)-1-((S)-1-(trans-2-(3-chlorop...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179782(CHEMBL382815 | PVKRRLF-NH2)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179806(CHEMBL379697 | N-((S)-1-((S)-1-(trans-2-(3-chlorop...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179802(CHEMBL203101 | trans-N-((S)-4-methyl-1-oxo-1-(tran...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179787(CHEMBL206396 | N-((S)-1-((S)-1-(trans-2-(3-chlorop...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179812(CHEMBL205197 | N-((S)-1-((S)-1-(trans-2-(3-chlorop...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179790(CHEMBL381396 | PVARRLFG)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179796(CHEMBL381307 | VKRRLFG)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179792(CHEMBL206769 | PVKRALFG)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179808((S)-2-[(S)-5-guanidino-2-(5-guanidino-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179805(CHEMBL380317 | N-((S)-1-((S)-1-(trans-2-(3-chlorop...)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179780(CHEMBL204947 | N-((S)-1-((S)-1-((S)-1-amino-3-(3-c...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179804(CHEMBL382403 | KRRLFG)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179811(CHEMBL208298 | N-((S)-1-((S)-1-(trans-2-(3-chlorop...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179785(CHEMBL206763 | RRLFG)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179807(CHEMBL199789 | PVKARLFG)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179783((S)-2-{(S)-5-Guanidino-2-[2-(4-guanidino-phenyl)-a...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179793(CHEMBL380423 | N-((S)-1-((S)-1-((S)-1-amino-3-(3-c...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179786((desNH2)-RRL-(3Cl)F-NH2 | CHEMBL206668)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179800((S)-N-((S)-1-(trans-2-(3-chlorophenyl)cyclohexylam...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179810(CHEMBL203774 | N-((S)-1-((S)-1-((S)-1-amino-3-(3-c...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179781((S)-2-[(S)-5-Guanidino-2-(5-guanidino-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179813(CHEMBL208012 | N-((S)-1-((S)-1-((S)-1-amino-3-(3-c...)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179809(CHEMBL203024 | PVKRRLAG)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179791((S)-2-[(S)-5-guanidino-2-(5-guanidino-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179799(1-((1S,5S,9S)-4-(((S)-1-((S)-1-((S)-1-amino-3-(3-c...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179788(CHEMBL383664 | PVKRRAFG)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50179794(CHEMBL382219 | N-((R)-1-((S)-1-(trans-2-(3-chlorop...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of CDK2/CyclinAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1JG7PubMed