Compile Data Set for Download or QSAR
Found 19 Enz. Inhib. hit(s) with all data for entry = 50017327
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180564(4-(4-bromo-2-fluorophenylamino)-N-(cyclopropylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180558(4-(4-bromo-2-fluorophenylamino)-5-fluoro-N-(2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180572(4-(4-bromo-2-fluorophenylamino)-5-fluoro-1-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180561(4-(4-bromo-2-fluorophenylamino)-5-fluoro-N-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180562(4-(4-bromo-2-fluorophenylamino)-N-(2-hydroxyethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180556(4-(4-bromo-2-fluorophenylamino)-N-(2-hydroxyethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180563(4-(4-bromo-2-fluorophenylamino)-5-fluoro-1-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180573(4-(4-bromo-2-fluorophenylamino)-N-ethoxy-5-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180566(4-(4-bromo-2-fluorophenylamino)-N-(cyclopropylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180571(4-(4-bromo-2-fluorophenylamino)-N-(cyclopropylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180570(4-(4-bromo-2-fluorophenylamino)-5-fluoro-N-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180560(4-(4-bromo-2-fluorophenylamino)-5-chloro-N-(2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180569(4-(4-bromo-2-fluorophenylamino)-N-ethoxy-1,5-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180567(4-(4-bromo-2-fluorophenylamino)-N-methoxy-1,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180568(4-(4-bromo-2-fluorophenylamino)-5-fluoro-N,1-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 118nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180574(4-(4-bromo-2-fluorophenylamino)-5-chloro-N-(cyclop...)copy SMILEScopy InChI
Affinity DataIC50: 124nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180557(4-(4-bromo-2-fluorophenylamino)-N-(cyclopropylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180565(4-(4-bromo-2-chlorophenylamino)-5,6-dichloro-N-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50180559(4-(4-bromo-2-chlorophenylamino)-5-chloro-N-(2-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 6.79E+3nMAssay Description:Inhibitory activity aginst MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BKQPubMed