Compile Data Set for Download or QSAR
Found 23 Enz. Inhib. hit(s) with all data for entry = 50018145
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191929(2-(4-(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191913(CHEMBL384350 | N-(2-methyl-4-(2-(pyrrolidin-1-yl)e...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191918(CHEMBL212552 | N-(2-methyl-4-(2-(piperidin-1-yl)et...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191924(CHEMBL377449 | N-(2-methyl-4-(2-morpholinoethyl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191922(CHEMBL212299 | trans-N1-(4-(1H-pyrrolo[2,3-b]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191925(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-N-o-tolylpyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191914(CHEMBL212833 | N-(2-chlorophenyl)-4-(1H-pyrrolo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191919(CHEMBL380301 | N-(2-bromophenyl)-4-(1H-pyrrolo[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191912(CHEMBL385478 | N-cyclohexyl-4-(1H-pyrrolo[2,3-b]py...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191928(1-(3-(2-(cyclohexylamino)pyrimidin-4-yl)-1H-pyrrol...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191916(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-N-p-tolylpyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191923(CHEMBL213023 | N-(2-methoxyphenyl)-4-(1H-pyrrolo[2...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191932(CHEMBL377048 | N-(2-fluorophenyl)-4-(1H-pyrrolo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191917(CHEMBL378768 | N-phenyl-4-(1H-pyrrolo[2,3-b]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191926(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-N-(2-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191920(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-N-m-tolylpyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191915(CHEMBL213277 | N-(2-ethylphenyl)-4-(1H-pyrrolo[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191921(CHEMBL215048 | N-cyclohexyl-4-(1-(methylsulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 128nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191931(2-(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 139nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191930(CHEMBL213207 | N-(cyclohexylmethyl)-4-(1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 151nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191911(CHEMBL212908 | trans-N1-(4-(2-methyl-1H-pyrrolo[2,...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191927(CHEMBL214055 | N-cyclohexyl-4-(1-methyl-1H-pyrrolo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50191910(CHEMBL212347 | N-cyclohexyl-4-(1-(2-(dimethylamino...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of CDK1/cyclinB by Flashplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571BNMPubMed