Compile Data Set for Download or QSAR
Found 86 Enz. Inhib. hit(s) with all data for entry = 50018147
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50398057(CHEMBL2181924)copy SMILEScopy InChI
Affinity DataKi:  0.00250nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50251208(CHEMBL4088272)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50405519(CHEMBL5278314)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50048866(1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:In vivo inhibitory activity against Angiotensin I converting enzyme was evaluated in renal hypertensive ratsMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50405520(CHEMBL1822601)copy SMILEScopy InChI
Affinity DataKi:  0.630nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50048866(1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...)copy SMILEScopy InChI
Affinity DataKi:  0.680nMAssay Description:Inhibitory activity against porcine plasma Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50405518(CHEMBL5291247)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50405523(CHEMBL5278355)copy SMILEScopy InChI
Affinity DataKi:  0.950nMAssay Description:Inhibition of human trypsin and the control activity being 7.3 umol/min/mgMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50170660(CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-me...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor determined as pA2 in guinea pig tracheaMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50569768(CHEMBL4860790)copy SMILES
Affinity DataKi:  1.60nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50038419(CHEMBL50112 | N-(1-Benzyl-piperidin-4-yl)-4-iodo-b...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor determined as pA2 in guinea pig tracheaMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50405517(CHEMBL5279451)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50405515(CHEMBL4792070)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:In vivo inhibitory activity against Angiotensin I converting enzyme was evaluated in renal hypertensive ratsMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50216057(CHEMBL226539 | N-[6,7-dimethoxy-3,4-dihydro-1H-iso...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50405522(CHEMBL5274755)copy SMILEScopy InChI
Affinity DataKi:  2.40nMAssay Description:Inhibition of human acrosin and control activity being 11.3 umol/min/mgMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor determined as pA2 in guinea pig tracheaMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50405512(CHEMBL5270434)copy SMILEScopy InChI
Affinity DataKi:  3.10nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor determined as pA2 in guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50445477(CHEMBL3104856)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405513(CHEMBL5274616)copy SMILEScopy InChI
Affinity DataKi:  3.70nMAssay Description:In vivo inhibitory activity against Angiotensin I converting enzyme was evaluated in renal hypertensive ratsMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405514(CHEMBL5273358)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibitory activity against porcine plasma Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50338990(1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piper...)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50569767(CHEMBL4858036)copy SMILES
Affinity DataKi:  5.40nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50405530(CHEMBL5283424)copy SMILEScopy InChI
Affinity DataKi:  6.20nMAssay Description:Inhibition of human trypsin and the control activity being 7.3 umol/min/mgMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50405518(CHEMBL5291247)copy SMILEScopy InChI
Affinity DataKi:  7.5nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50405516(FMI | MIN-101 FREE BASE | ROLUPERIDONE | Roluperid...)copy SMILEScopy InChI
Affinity DataKi:  7.5nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50210268(CHEMBL3984952)copy SMILEScopy InChI
Affinity DataKi:  7.70nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50445476(CHEMBL3104857)copy SMILEScopy InChI
Affinity DataKi:  7.80nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50405528(CHEMBL5291479)copy SMILEScopy InChI
Affinity DataKi:  7.90nMAssay Description:Inhibition of human trypsin and the control activity being 7.3 umol/min/mgMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50405519(CHEMBL5278314)copy SMILEScopy InChI
Affinity DataKi:  7.90nMAssay Description:Inhibition of human acrosin and control activity being 11.3 umol/min/mgMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405516(FMI | MIN-101 FREE BASE | ROLUPERIDONE | Roluperid...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:In vivo inhibitory activity against Angiotensin I converting enzyme was evaluated in renal hypertensive ratsMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50035105(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:In vivo inhibitory activity against Angiotensin I converting enzyme was evaluated in renal hypertensive ratsMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50092741(CHEMBL338468 | N-(2-Diethylamino-ethyl)-3-iodo-4-m...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50035105(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50405518(CHEMBL5291247)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50405520(CHEMBL1822601)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of human trypsin and the control activity being 7.3 umol/min/mgMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50405525(CHEMBL5267888)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Inhibition of human acrosin and control activity being 11.3 umol/min/mgMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50405511(Edonerpic | J2.972.359A | T-817)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50405517(CHEMBL5279451)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50396352(CHEMBL2170062)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor determined as pA2 in guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Compound was evaluated for inhibition of porcine plasma Angiotensin I converting enzyme by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50405526(CHEMBL5277371)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Inhibition of human trypsin and the control activity being 7.3 umol/min/mgMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50405529(CHEMBL4650909)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of human trypsin and the control activity being 7.3 umol/min/mgMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50216057(CHEMBL226539 | N-[6,7-dimethoxy-3,4-dihydro-1H-iso...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50038419(CHEMBL50112 | N-(1-Benzyl-piperidin-4-yl)-4-iodo-b...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:In vitro inhibitory activity against beta-2 adrenergic receptor determined as pA2 in guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50405517(CHEMBL5279451)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50405527(CHEMBL5282093)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Inhibition of human trypsin and the control activity being 7.3 umol/min/mgMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50405517(CHEMBL5279451)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50405513(CHEMBL5274616)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Inhibitory activity against porcine plasma Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50445476(CHEMBL3104857)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Inhibition of purified human kidney thiopurine methyltransferase (TPMT)More data for this Ligand-Target Pair
In DepthDetails
Displayed 1 to 50 (of 86 total ) | Next | Last >>
Jump to: