Compile Data Set for Download or QSAR
Found 28 Enz. Inhib. hit(s) with all data for entry = 50018232
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM439497(US10633379, Example 35 | US10633379, Example 82)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM439497(US10633379, Example 35 | US10633379, Example 82)copy SMILEScopy InChI
Affinity DataKi:  520nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50407714(CHEMBL5269983)copy SMILEScopy InChI
Affinity DataIC50: 0.420nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM50407715(CHEMBL5290597)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50569836(CHEMBL4850926)copy SMILES
Affinity DataIC50: 11nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHistone deacetylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50569836(CHEMBL4850926)copy SMILES
Affinity DataIC50: 21nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50551271(CHEMBL4747491)copy SMILES
Affinity DataIC50: 22nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat thoracic aorta (Alpha-1D adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50407714(CHEMBL5269983)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50551271(CHEMBL4747491)copy SMILES
Affinity DataIC50: 109nMAssay Description:Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50582039(CHEMBL5080097)copy SMILES
Affinity DataIC50: 130nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50407713(CHEMBL5082762)copy SMILEScopy InChI
Affinity DataIC50: 163nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
In DepthDetails
TargetALK tyrosine kinase receptor(Homo sapiens (Human))TBA
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat thoracic aorta (Alpha-1D adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50597849(CHEMBL5205994)copy SMILES
Affinity DataIC50: 379nMAssay Description:Inhibitory activity against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50597849(CHEMBL5205994)copy SMILES
Affinity DataIC50: 440nMAssay Description:Inhibitory activity against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50407713(CHEMBL5082762)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
In DepthDetails
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50597849(CHEMBL5205994)copy SMILES
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory activity against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50582039(CHEMBL5080097)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:pA2 for NK2 receptor of Human bladderMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50407718(CHEMBL5289364)copy SMILEScopy InChI
Affinity DataKd:  180nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat thoracic aorta (Alpha-1D adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50512415(CHEMBL4226052)copy SMILEScopy InChI
Affinity DataKd:  90nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50593635(CHEMBL5205867)copy SMILES
Affinity DataKd:  2nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50407716(CHEMBL5277866)copy SMILEScopy InChI
Affinity DataKd:  44nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat thoracic aorta (Alpha-1D adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50407717(CHEMBL5278246)copy SMILEScopy InChI
Affinity DataKd:  382nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50581595(CHEMBL4215078)copy SMILES
Affinity DataKd:  9.60nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat thoracic aorta (Alpha-1D adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50581595(CHEMBL4215078)copy SMILES
Affinity DataKd:  7.60nMAssay Description:Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50407717(CHEMBL5278246)copy SMILEScopy InChI
Affinity DataKd:  120nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50593635(CHEMBL5205867)copy SMILES
Affinity DataKd:  301nMAssay Description:pA2 for NK2 receptor of rabbit pulmonary arteryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)copy SMILEScopy InChI
Affinity DataKd:  37nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat thoracic aorta (Alpha-1D adrenoceptor)More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))TBA
LigandPNGBDBM50512415(CHEMBL4226052)copy SMILEScopy InChI
Affinity DataKd:  28nMAssay Description:Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails