Compile Data Set for Download or QSAR
Found 48 Enz. Inhib. hit(s) with all data for entry = 50018236
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407800(CHEMBL5291138)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50346870(CHEMBL1797647)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50346870(CHEMBL1797647)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50586363(CHEMBL5079374)copy SMILES
Affinity DataKi:  140nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50407795(CHEMBL5281080)copy SMILEScopy InChI
Affinity DataKi:  157nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50407796(CHEMBL1255711)copy SMILEScopy InChI
Affinity DataKi:  193nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50407722(CHEMBL5287743)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407723(CHEMBL5274037)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50407721(CHEMBL5266466)copy SMILEScopy InChI
Affinity DataKi:  2.84E+4nMAssay Description:Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407800(CHEMBL5291138)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50986(MLS000563434 | SMR000232286 | cid_160876)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50594961(CHEMBL5201233)copy SMILES
Affinity DataIC50: 140nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50587726(CHEMBL3401107)copy SMILES
Affinity DataIC50: 183nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM20461((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50441978(CHEMBL2334501)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.81E+3nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407799(CHEMBL5282190)copy SMILEScopy InChI
Affinity DataIC50: 2.98E+3nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50242173((2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 3.01E+3nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407801(CHEMBL5284058)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407720(CHEMBL5279958)copy SMILEScopy InChI
Affinity DataIC50: 5.27E+3nMAssay Description:Blocking activity was assessed by antagonism of (-)-noradrenaline induced contraction of rat prostatic vas deferens (alpha1A adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407803(CHEMBL5274732)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407805(CHEMBL5274387)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407807(CHEMBL5270254)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+3nMAssay Description:Antagonistic activity against calcitonin gene related peptide receptor determined by measuring the formation of cyclic AMP in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407798(CHEMBL3134309)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407802(CHEMBL5271269)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407808(CHEMBL5283677)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against calcitonin gene related peptide receptor determined by measuring the formation of cyclic AMP in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50158878(CHEMBL3785551)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+4nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407719(CHEMBL5281939)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor)More data for this Ligand-Target Pair
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50407797(CHEMBL5290659)copy SMILEScopy InChI
Affinity DataIC50: 1.61E+4nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))TBA
LigandPNGBDBM50594961(CHEMBL5201233)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM50594961(CHEMBL5201233)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50445351(NAMOLINE)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+4nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))TBA
LigandPNGBDBM50407807(CHEMBL5270254)copy SMILEScopy InChI
Affinity DataIC50: 6.39E+4nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM50407802(CHEMBL5271269)copy SMILEScopy InChI
Affinity DataIC50: 6.57E+4nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))TBA
LigandPNGBDBM50407801(CHEMBL5284058)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+4nMAssay Description:Antagonistic activity against calcitonin gene related peptide receptor determined by measuring the formation of cyclic AMP in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))TBA
LigandPNGBDBM50407805(CHEMBL5274387)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+4nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM50407803(CHEMBL5274732)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+5nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))TBA
LigandPNGBDBM50407808(CHEMBL5283677)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+5nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))TBA
LigandPNGBDBM50407803(CHEMBL5274732)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+5nMAssay Description:Antagonistic activity against calcitonin gene related peptide receptor determined by measuring the formation of cyclic AMP in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM50407801(CHEMBL5284058)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+5nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))TBA
LigandPNGBDBM50407802(CHEMBL5271269)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+5nMAssay Description:Antagonistic activity against calcitonin gene related peptide receptor determined by measuring the formation of cyclic AMP in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM50407805(CHEMBL5274387)copy SMILEScopy InChI
Affinity DataIC50: 2.26E+5nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM50407807(CHEMBL5270254)copy SMILEScopy InChI
Affinity DataIC50: 2.98E+5nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM50407808(CHEMBL5283677)copy SMILEScopy InChI
Affinity DataIC50: 3.44E+5nMAssay Description:Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50507295(CHEMBL1232432)copy SMILEScopy InChI
Affinity DataKd:  243nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))TBA
LigandPNGBDBM50594962(CHEMBL5177178)copy SMILES
Affinity DataKd:  1.40E+5nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails