Compile Data Set for Download or QSAR
Found 140 Enz. Inhib. hit(s) with all data for entry = 50018465
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR Y290L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR Y290L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR N27A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from GnRHR F272L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from GnRHR F272L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR N27A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR Q208E mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR Q208E mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR L300A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR L300A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122655(CHEMBL280212 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from GnRHR F272L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR F309L mutant expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR F309L mutant expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR F309Q mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR Y284L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122655(CHEMBL280212 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR D302N mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122655(CHEMBL280212 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR D302A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50196040(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from GnRHR F272L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122655(CHEMBL280212 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR Y290L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122655(CHEMBL280212 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR L300A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR F313L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR H306A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR F313L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR M24I mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122655(CHEMBL280212 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR N27A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR F309Q mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50133849(CHEMBL332355 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from GnRHR F272L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50196040(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR N27A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122655(CHEMBL280212 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR Q208E mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50133849(CHEMBL332355 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR N27A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR H306A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50133856(1-(2,6-Difluoro-benzyl)-5-{[methyl-(2-pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR D302N mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR Y284L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR D302N mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50133856(1-(2,6-Difluoro-benzyl)-5-{[methyl-(2-pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Displacement of [125I-His5, D-Tyr6]GnRH from GnRHR F272L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50133849(CHEMBL332355 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR Y290L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50133856(1-(2,6-Difluoro-benzyl)-5-{[methyl-(2-pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR D302A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR H306E mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR D302A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50196040(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR Q208E mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50196040(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR Y290L mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122655(CHEMBL280212 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR F309L mutant expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR H306E mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR M24I mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50133856(1-(2,6-Difluoro-benzyl)-5-{[methyl-(2-pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR L300A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR D302N mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50133849(CHEMBL332355 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR D302N mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR D302A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50196040(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR L300A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50133856(1-(2,6-Difluoro-benzyl)-5-{[methyl-(2-pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Displacement of [His5, D-Tyr6]GnRH from GnRHR N27A mutant expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CFNPubMed
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