Compile Data Set for Download or QSAR
Found 70 Enz. Inhib. hit(s) with all data for entry = 50018895
TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)copy SMILEScopy InChI
In DepthDetails
TargetCyclin-dependent kinase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)copy SMILEScopy InChI
In DepthDetails
TargetFocal adhesion kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50246060(CHEMBL472212 | CHEMBL541649 | D3RKN_6 | N-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCyclin-dependent kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)copy SMILEScopy InChI
In DepthDetails
TargetCyclin-dependent kinase 9(Homo sapiens (Human))TBA
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)copy SMILEScopy InChI
In DepthDetails
TargetSerine/threonine-protein kinase PLK2(Homo sapiens (Human))TBA
LigandPNGBDBM50613682(CHEMBL5276995)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM26479(4-N-(3-methyl-1H-indazol-6-yl)-2-N-(3,4,5-trimetho...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))TBA
LigandPNGBDBM50427453(CHEMBL2322228 | US10308662, Compound 28 | US950578...)copy SMILEScopy InChI
In DepthDetails
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50246060(CHEMBL472212 | CHEMBL541649 | D3RKN_6 | N-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))TBA
LigandPNGBDBM50099349(2-(2,3-Dimethyl-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50099349(2-(2,3-Dimethyl-phenoxy)-4-[5-(4-fluoro-phenyl)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In DepthDetails
TargetRibosomal protein S6 kinase alpha-6(Homo sapiens (Human))TBA
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)copy SMILEScopy InChI
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In DepthDetails
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)copy SMILEScopy InChI
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In DepthDetails
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))TBA
LigandPNGBDBM50431381(FOSTAMATINIB | R-788 Free acid | R-935788 Free aci...)copy SMILEScopy InChI
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In DepthDetails
TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))TBA
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)copy SMILEScopy InChI
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In DepthDetails
TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))TBA
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)copy SMILEScopy InChI
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In DepthDetails
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))TBA
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)copy SMILEScopy InChI
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50099334(4-[5-(4-Fluoro-phenyl)-3-piperidin-4-yl-3H-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))TBA
LigandPNGBDBM50099334(4-[5-(4-Fluoro-phenyl)-3-piperidin-4-yl-3H-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50427457(CHEMBL2326952 | US10308662, Compound 25 | US950578...)copy SMILEScopy InChI
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
In DepthDetails
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM8246(3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCyclin-dependent kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In DepthDetails DrugBank
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))TBA
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)copy SMILEScopy InChI
Affinity DataIC50: 31nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50365463(CHEMBL1232461)copy SMILEScopy InChI
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain testis-specific protein(Homo sapiens (Human))TBA
LigandPNGBDBM50365262((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)copy SMILEScopy InChI
Affinity DataIC50: 35nMMore data for this Ligand-Target Pair
In DepthDetails
TargetEpidermal growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50613683(CHEMBL5270270)copy SMILES
Affinity DataIC50: 44nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50044784(CHEBI:79090 | SB-202190 | US10865384, Compound SB2...)copy SMILEScopy InChI
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))TBA
LigandPNGBDBM50613682(CHEMBL5276995)copy SMILES
Affinity DataIC50: 56nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM8246(3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 94nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCyclin-dependent kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))TBA
LigandPNGBDBM50044784(CHEBI:79090 | SB-202190 | US10865384, Compound SB2...)copy SMILEScopy InChI
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain testis-specific protein(Homo sapiens (Human))TBA
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)copy SMILEScopy InChI
Affinity DataIC50: 130nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM192755(TG101209 | US11279703, TABLE 6.171 | US11643396, E...)copy SMILEScopy InChI
Affinity DataIC50: 169nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 170nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))TBA
LigandPNGBDBM50427453(CHEMBL2322228 | US10308662, Compound 28 | US950578...)copy SMILEScopy InChI
Affinity DataIC50: 280nMMore data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain testis-specific protein(Homo sapiens (Human))TBA
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 290nMMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))TBA
LigandPNGBDBM50613680(CHEMBL5285509)copy SMILES
Affinity DataIC50: 410nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))TBA
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)copy SMILES
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50427457(CHEMBL2326952 | US10308662, Compound 25 | US950578...)copy SMILEScopy InChI
Affinity DataIC50: 714nMMore data for this Ligand-Target Pair
In DepthDetails
TargetBromodomain testis-specific protein(Homo sapiens (Human))TBA
LigandPNGBDBM50613679(CHEMBL5287725)copy SMILES
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50427457(CHEMBL2326952 | US10308662, Compound 25 | US950578...)copy SMILEScopy InChI
Affinity DataIC50: 1.17E+3nMMore data for this Ligand-Target Pair
In DepthDetails
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