Compile Data Set for Download or QSAR
Found 48 Enz. Inhib. hit(s) with all data for entry = 50019137
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM302860((2S)-1-(3-Thienyl)propan-2-ol | US9598431, 3)copy SMILEScopy InChI
Affinity DataKi:  17nMMore data for this Ligand-Target Pair
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM351740(US9796710, Compound 33)copy SMILEScopy InChI
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50594741(CHEMBL5205088)copy SMILES
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615657(CHEMBL4099342)copy SMILES
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615658(CHEMBL5276516)copy SMILES
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615648(CHEMBL5270756)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50509565(CHEMBL3558130)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615651(CHEMBL5277587)copy SMILES
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615659(CHEMBL5272739)copy SMILES
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM412666((S)-N-((5-(ethylsulfonyl)pyridin-2-yl)methyl)-7-is...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
PDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50509558(CHEMBL4449356)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615654(CHEMBL5270326)copy SMILES
Affinity DataIC50: 4.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM189897(US10227346, Example 23 | US10426135, Example 23 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615660(CHEMBL5280104)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50106301(CHEMBL3598140)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMMore data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615657(CHEMBL4099342)copy SMILES
Affinity DataIC50: 6.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615662(CHEMBL5279266)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615662(CHEMBL5279266)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615656(CHEMBL5273710)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50403298(CHEMBL5187263)copy SMILEScopy InChI
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615649(CHEMBL5287608)copy SMILES
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM412666((S)-N-((5-(ethylsulfonyl)pyridin-2-yl)methyl)-7-is...)copy SMILEScopy InChI
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
PDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615660(CHEMBL5280104)copy SMILES
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615650(CHEMBL5267150)copy SMILES
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM412666((S)-N-((5-(ethylsulfonyl)pyridin-2-yl)methyl)-7-is...)copy SMILEScopy InChI
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
PDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM302860((2S)-1-(3-Thienyl)propan-2-ol | US9598431, 3)copy SMILEScopy InChI
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615662(CHEMBL5279266)copy SMILES
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM546675(US11292781, Compound T158)copy SMILES
Affinity DataIC50: 36nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615653(CHEMBL5279576)copy SMILES
Affinity DataIC50: 37nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615645(CHEMBL5270647)copy SMILES
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50594740(CHEMBL5205826)copy SMILES
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50594740(CHEMBL5205826)copy SMILES
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50575029(CHEMBL4864604)copy SMILES
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM546551(US11292781, Compound T37)copy SMILES
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615647(CHEMBL5290286)copy SMILES
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM546635(US11292781, Compound T118)copy SMILES
Affinity DataIC50: 71nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615655(CHEMBL5288192)copy SMILES
Affinity DataIC50: 89nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615652(CHEMBL5290173)copy SMILES
Affinity DataIC50: 97nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM292717(US10106501, Example A1)copy SMILEScopy InChI
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615646(CHEMBL5290695)copy SMILES
Affinity DataIC50: 115nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM546688(US11292781, Compound T170)copy SMILES
Affinity DataIC50: 245nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50005410(CHEMBL139197 | CHEMBL2137199)copy SMILEScopy InChI
Affinity DataIC50: 320nMMore data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM50615661(CHEMBL5280496)copy SMILES
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM480761(US10905687, Compound 18 | US20230277527, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMMore data for this Ligand-Target Pair
TargetNuclear receptor ROR-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM480763(US10905687, Compound 21 | US20230277527, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))TBA
LigandPNGBDBM491945((S)—N-(2-Hydroxy-2-methylpropyl)-4-(2-methylp...)copy SMILEScopy InChI
Affinity DataKd:  0.170nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails