Compile Data Set for Download or QSAR
Found 13 Enz. Inhib. hit(s) with all data for entry = 50019562
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205734(1-(6-thiophen-2-yl-pyridazin-3-yl)-piperidine-4-ca...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Displacement of [125I]MIP1beta from CCR5 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205735(CHEMBL219770 | N-(2-methyl-4-((4-methylpiperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.41E+4nMAssay Description:Displacement of [125I]MIP1beta from CCR5 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205736(2-(4-benzyl-5-(2-(piperidin-1-yl)ethyl)-4H-1,2,4-t...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Displacement of [125I]MIP1beta from CCR5 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205732(1-(3-diethylamino-propylamino)-3-methyl-2-(2-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.24E+4nMAssay Description:Displacement of [125I]MIP1beta from CCR5 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205738(2-(4-oxo-3-(3-(piperidin-1-yl)propyl)-3,4-dihydroq...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+4nMAssay Description:Displacement of [125I]MIP1beta from CCR5 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205737(1-((1-(4-fluorobenzyl)-1H-tetrazol-5-yl)(2-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 7.94E+4nMAssay Description:Displacement of [125I]MIP1beta from CCR5 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205733(CHEMBL219769 | N-(1-benzylpiperidin-4-yl)-2-(5-met...)copy SMILEScopy InChI
Affinity DataIC50: 2.69E+5nMAssay Description:Displacement of [125I]MIP1beta from CCR5 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205737(1-((1-(4-fluorobenzyl)-1H-tetrazol-5-yl)(2-fluorop...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at CCR5 expressed in CHO-K1 cells in aqeuorin based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205733(CHEMBL219769 | N-(1-benzylpiperidin-4-yl)-2-(5-met...)copy SMILEScopy InChI
Affinity DataEC50:  1.35E+4nMAssay Description:Agonist activity at CCR5 expressed in CHO-K1 cells in aqeuorin based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205732(1-(3-diethylamino-propylamino)-3-methyl-2-(2-methy...)copy SMILEScopy InChI
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at CCR5 expressed in CHO-K1 cells in aqeuorin based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205735(CHEMBL219770 | N-(2-methyl-4-((4-methylpiperazin-1...)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at CCR5 expressed in CHO-K1 cells in aqeuorin based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205734(1-(6-thiophen-2-yl-pyridazin-3-yl)-piperidine-4-ca...)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at CCR5 expressed in CHO-K1 cells in aqeuorin based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
CNRS UMR 7175-LC1

Curated by ChEMBL
LigandPNGBDBM50205736(2-(4-benzyl-5-(2-(piperidin-1-yl)ethyl)-4H-1,2,4-t...)copy SMILEScopy InChI
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at CCR5 expressed in CHO-K1 cells in aqeuorin based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1XK6PubMed