Compile Data Set for Download or QSAR
Found 39 Enz. Inhib. hit(s) with all data for entry = 50020232
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211482(1-(2,4-difluoro-phenyl)-3-(3,5a,10-trimethyl-2-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211496(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211478(2-(7-methoxy-5,8-dimethyl-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211491(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211495(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211488(CHEMBL376759 | N-(furan-2-ylmethyl)-2-(7-methoxy-5...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211483(3,4,5-trimethoxy-N-(3,5a,10-trimethyl-2-oxo-2,3,3a...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211489(2-(7-(2-(dimethylamino)ethoxy)-5,8-dimethyl-1,2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211491(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211484(1-(3-methylsulfanyl-phenyl)-3-(3,5a,10-trimethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211496(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211481(CHEMBL226814 | benzo[1,3]dioxole-5-carboxylic acid...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211479(1-benzyl-3-(3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a,...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211490(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211484(1-(3-methylsulfanyl-phenyl)-3-(3,5a,10-trimethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211487(CHEMBL227301 | N-tert-butyl-2-(7-methoxy-5,8-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211485(2-(2-methoxy-phenyl)-N-(3,5a,10-trimethyl-2-oxo-2,...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211478(2-(7-methoxy-5,8-dimethyl-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211480(4-methoxy-N-(3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211495(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211482(1-(2,4-difluoro-phenyl)-3-(3,5a,10-trimethyl-2-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211494(2-(7-methoxy-5,8-dimethyl-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211492(CHEMBL227139 | cyclopentanecarboxylic acid (3,5a,1...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211490(2-(5,8-dimethyl-7-propoxy-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211486(4-methyl-[1,2,3]thiadiazole-5-carboxylic acid (3,5...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211492(CHEMBL227139 | cyclopentanecarboxylic acid (3,5a,1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211488(CHEMBL376759 | N-(furan-2-ylmethyl)-2-(7-methoxy-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211487(CHEMBL227301 | N-tert-butyl-2-(7-methoxy-5,8-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211493(CHEMBL373949 | N-cyclopentyl-2-[7-(2-methoxy-ethox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211479(1-benzyl-3-(3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211480(4-methoxy-N-(3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211489(2-(7-(2-(dimethylamino)ethoxy)-5,8-dimethyl-1,2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211486(4-methyl-[1,2,3]thiadiazole-5-carboxylic acid (3,5...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211481(CHEMBL226814 | benzo[1,3]dioxole-5-carboxylic acid...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211493(CHEMBL373949 | N-cyclopentyl-2-[7-(2-methoxy-ethox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211494(2-(7-methoxy-5,8-dimethyl-1,2,3,4-tetrahydronaphth...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211485(2-(2-methoxy-phenyl)-N-(3,5a,10-trimethyl-2-oxo-2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211483(3,4,5-trimethoxy-N-(3,5a,10-trimethyl-2-oxo-2,3,3a...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed