Compile Data Set for Download or QSAR
Found 38 Enz. Inhib. hit(s) with all data for entry = 50021389
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224129(CHEMBL237626 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224118(CHEMBL237592 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224128(CHEMBL238027 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224122(CHEMBL398382 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224113(CHEMBL237811 | ethyl-2-Methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of COX2 in LPS-induced monocyte assessed as PGE2 production in human whole bloodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224124(CHEMBL237813 | ethyl-2-methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224125(CHEMBL393159 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224114(CHEMBL441132 | Ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224127(CHEMBL398384 | ethyl-2-methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224118(CHEMBL237592 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of COX2 in LPS-induced monocyte assessed as PGE2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224126(CHEMBL398383 | Ehyl-2-methyl-1-[4-(methylsulfonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224119(CHEMBL391113 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224117(CHEMBL438147 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as TXB2 productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224118(CHEMBL237592 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as TXB2 productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224127(CHEMBL398384 | ethyl-2-methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224130(CHEMBL237183 | ethyl-2-methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224129(CHEMBL237626 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224131(CHEMBL237182 | ethyl-2-methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224126(CHEMBL398383 | Ehyl-2-methyl-1-[4-(methylsulfonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224125(CHEMBL393159 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224128(CHEMBL238027 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224115(CHEMBL238033 | ethyl-2-Methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224132(CHEMBL238031 | ethyl-2-methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224124(CHEMBL237813 | ethyl-2-methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224113(CHEMBL237811 | ethyl-2-Methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224119(CHEMBL391113 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224123(CHEMBL237391 | ehyl-2-methyl-1-[4-(methylsulfonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224121(CHEMBL391020 | ethyl-2-methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224122(CHEMBL398382 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224120(CHEMBL236159 | ethyl-2-methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224118(CHEMBL237592 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224114(CHEMBL441132 | Ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224116(CHEMBL393160 | ethyl-2-methyl-1-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Università La Sapienza

Curated by ChEMBL
LigandPNGBDBM50224117(CHEMBL438147 | ethyl-2-methyl-5-[4-(methylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FV8PubMed