Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with all data for entry = 50025161
TargetFocal adhesion kinase 1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human A431 cells by ELISAMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human FG cells after 60 mins by western blot analysisMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human SKOV3 cells after 60 mins by western blot analysisMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human PC3 cells after 60 mins by western blot analysisMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 197nMAssay Description:Inhibition of human CDK7/cyclinH/MAT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GQHPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human L3.6pl cells after 60 mins by western blot analysisMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 486nMAssay Description:Inhibition of human CDK1/cyclinBMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GQHPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GQHPubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
University of Virginia

Curated by ChEMBL
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Pyk2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67GQHPubMed