Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with all data for entry = 50025550
TargetThymidine phosphorylase(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of human recombinant thymidine phosphorylase by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50134399(1,7-Dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dione | 7...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of bovine xanthine oxidase using hypoxanthine as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZDPPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50134399(1,7-Dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dione | 7...)copy SMILEScopy InChI
Affinity DataKi:  7.00E+4nMAssay Description:Inhibition of bovine xanthine oxidase using xanthine as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZDPPubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122764(2-Amino-1-(5-bromo-2,6-dioxo-1,2,3,6-tetrahydro-py...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZDPPubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant thymidine phosphorylase by [3H]thymidine incorporation assayMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50122770(6-Amino-5-bromo-1H-pyrimidine-2,4-dione | 6-Amino-...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZDPPubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
The University of Manchester

Curated by ChEMBL
LigandPNGBDBM50134399(1,7-Dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dione | 7...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZDPPubMed