Compile Data Set for Download or QSAR
Found 28 Enz. Inhib. hit(s) with all data for entry = 50026010
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataKi:  2.51E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataKi:  2.71E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataKi:  2.75E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataKi:  2.87E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataKi:  3.41E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266160(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataKi:  3.42E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266159(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataKi:  3.63E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266160(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataKi:  4.05E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)copy SMILEScopy InChI
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)copy SMILEScopy InChI
Affinity DataKi:  4.44E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266159(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataKi:  3.55E+5nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266159(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 4.55E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266159(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266160(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266160(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataIC50: 5.71E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed