Compile Data Set for Download or QSAR
Found 38 Enz. Inhib. hit(s) with all data for entry = 50026300
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243934(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,6-triflu...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244291(4-[(2-Fluorobenzyl)amino]-2-[(4-morpholin-4-ylphen...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243884(4-[(2,5-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243933(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,5-triflu...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244292(4-[(3-Fluorobenzyl)amino]-2-[(4-morpholin-4-ylphen...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243882(4-[(2,3-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243885(4-[(2,6-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243932(4-[(3,5-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244256(4-Benzylamino-2-{[4-(4-methylpiperazin-1-yl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244258(4-(benzylamino)-2-(4-morpholinophenylamino)pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244257(4-Benzylamino-2-[(4-piperazin-1-ylphenyl)amino]-py...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244331(4-[(2-Chlorobenzyl)amino]-2-[(4-morpholin-4-ylphen...)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244329(4-[(2-Methoxybenzyl)amino]-2-[(4-morpholin-4-ylphe...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244294(4-[(2-Methylbenzyl)amino]-2-[(4-morpholin-4-ylphen...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244223(4-Benzylamino-2-{[4-(4-hydroxypiperidin-1-yl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244259(4-Benzylamino-2-{[4-(1-methylpiperidin-4-yl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243794(4-[(3-Hydroxybenzyl)amino]-2-[(4-morpholin-4-ylphe...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50197554(2-(3-chloro-4-hydroxyphenethylamino)-4-(benzylamin...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244330(4-[(2-Hydroxybenzyl)amino]-2-[(4-morpholin-4-ylphe...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244369(4-{[2-(Methylsulfanyl)benzyl]amino}-2-[(4-morpholi...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243725(4-[(3-Methoxybenzyl)amino]-2-[(4-morpholin-4-ylphe...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244332(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2-trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243723(4-[(3-Chlorobenzyl)amino]-2-[(4-morpholin-4-ylphen...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244366(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2-nitrobenzy...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244189(4-(Benzylamino)-2-{[2-(3,5-dichloro-4-hydroxypheny...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244191(4-Benzylamino-2-{[4-(3-hydroxypropyl)phenyl]amino}...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243934(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,6-triflu...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50197567(2-(4-hydroxyphenethylamino)-4-(benzylamino)pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244190(4-Benzylamino-2-{[4-(2-hydroxyethyl)phenyl]amino}p...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244222(4-(Benzylamino)-2-{[4-(3-hydroxypyrrolidine-1-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244225(4-Benzylamino-2-[(4-piperidin-1-ylphenyl)amino]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243724(2-[(4-Morpholin-4-ylphenyl)amino]-4-[(3-trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244367(4-[(2-Aminobenzyl)amino]-2-[(4-morpholin-4-ylpheny...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243883(4-[(2,4-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244293(4-[(4-Fluorobenzyl)amino]-2-[(4-morpholin-4-ylphen...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244224(4-(Benzylamino)-2-[(4-pyrrolidine-1-ylphenyl)-amin...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50243722(4-{[2-(Methylsulfonyl)benzyl]amino}-2-[(4-morpholi...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed
TargetSignal transducer and activator of transcription 6(Homo sapiens (Human))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50244368(4-{[2-(Acetylamino)benzyl]amino}-2-[(4-morpholin-4...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of STAT6 activation (unknown origin) in FW4 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD6Z7HPubMed