Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with all data for entry = 50026562
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263049((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataKi:  550nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263049((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataKi:  670nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263049((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)copy SMILEScopy InChI
Affinity DataKi:  2.33E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)copy SMILEScopy InChI
Affinity DataKi:  3.25E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)copy SMILEScopy InChI
Affinity DataKi:  4.15E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263049((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263049((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263091((R)-2-(((2R,3R,4R)-3,4-dihydroxy-1-methyl-5-oxopyr...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263049((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263091((R)-2-(((2R,3R,4R)-3,4-dihydroxy-1-methyl-5-oxopyr...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263048((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263047((R)-2-(((2R,3R,4S)-3,4-dihydroxypyrrolidin-2-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263050((R)-2-(((2R,3R,4R)-3,4-dihydroxy-5-oxopyrrolidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263048((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263047((R)-2-(((2R,3R,4S)-3,4-dihydroxypyrrolidin-2-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263091((R)-2-(((2R,3R,4R)-3,4-dihydroxy-1-methyl-5-oxopyr...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263050((R)-2-(((2R,3R,4R)-3,4-dihydroxy-5-oxopyrrolidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263047((R)-2-(((2R,3R,4S)-3,4-dihydroxypyrrolidin-2-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263048((3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique Fédérale de Lausanne

Curated by ChEMBL
LigandPNGBDBM50263050((R)-2-(((2R,3R,4R)-3,4-dihydroxy-5-oxopyrrolidin-2...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+5nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D0JPubMed