TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha7 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 410nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 350nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 18nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 1.00E+5nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 1.20E+3nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 48nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 6nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 270nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 220nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 1.30E+3nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 4.60E+3nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 33nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 34nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha3beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha3beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha3beta4 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha3beta4 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Amgen Inc.
Curated by ChEMBL
Amgen Inc.
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activation of rat alpha4beta2 nAChR by fluorescence assayMore data for this Ligand-Target Pair