Compile Data Set for Download or QSAR
Found 35 Enz. Inhib. hit(s) with all data for entry = 50028181
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248064(2,4-dichloro-N-((4-(2-hydroxycyclohexyl)-1-(propyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248062(2,4-dichloro-N-((1-(propylsulfonyl)-4-((tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248100((2,4-dichloro-N-((1-(propylsulfonyl)-4-(pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248128(2,4-dichloro-N-((1-(2-fluoropropylsulfonyl)-4-(pyr...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248097(2-(4-((2,4-dichlorobenzamido)methyl)-1-(propylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248063(2,4-dichloro-N-((4-(2-methoxyethyl)-1-(propylsulfo...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248099(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(propylsu...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248098(CHEMBL462148 | N-((4-(azetidin-1-yl)-1-(propylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248130(2,4-dichloro-N-((1-(ethylsulfonyl)-4-(pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248162(2,4-dichloro-N-((1-(N,N-dimethylsulfamoyl)-4-(pyri...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248127(2,4-dichloro-N-((1-(2-hydroxypropylsulfonyl)-4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248159(CHEMBL463024 | N-((1-(butylsulfonyl)-4-(pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248160(2,4-dichloro-N-((1-(cyclopropylsulfonyl)-4-(pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248161(2,4-dichloro-N-((1-(isopropylsulfonyl)-4-(pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248129(2,4-dichloro-N-((1-(methylsulfonyl)-4-(pyridin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248208(2,4-dichloro-N-((4-(pyridin-2-yl)-1-(2,2,2-trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248207(2,4-dichloro-N-((4-(pyridin-2-yl)-1-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248064(2,4-dichloro-N-((4-(2-hydroxycyclohexyl)-1-(propyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Glyt2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248130(2,4-dichloro-N-((1-(ethylsulfonyl)-4-(pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Glyt2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248100((2,4-dichloro-N-((1-(propylsulfonyl)-4-(pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Glyt2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248099(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(propylsu...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Glyt2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248063(2,4-dichloro-N-((4-(2-methoxyethyl)-1-(propylsulfo...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Glyt2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248160(2,4-dichloro-N-((1-(cyclopropylsulfonyl)-4-(pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Glyt2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248062(2,4-dichloro-N-((1-(propylsulfonyl)-4-((tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of taurine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248063(2,4-dichloro-N-((4-(2-methoxyethyl)-1-(propylsulfo...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of taurine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248064(2,4-dichloro-N-((4-(2-hydroxycyclohexyl)-1-(propyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of taurine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248099(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(propylsu...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of taurine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248100((2,4-dichloro-N-((1-(propylsulfonyl)-4-(pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of taurine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248129(2,4-dichloro-N-((1-(methylsulfonyl)-4-(pyridin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of taurine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248130(2,4-dichloro-N-((1-(ethylsulfonyl)-4-(pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of taurine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248160(2,4-dichloro-N-((1-(cyclopropylsulfonyl)-4-(pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of taurine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent taurine transporter(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248128(2,4-dichloro-N-((1-(2-fluoropropylsulfonyl)-4-(pyr...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of taurine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248129(2,4-dichloro-N-((1-(methylsulfonyl)-4-(pyridin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Glyt2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248128(2,4-dichloro-N-((1-(2-fluoropropylsulfonyl)-4-(pyr...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Glyt2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248062(2,4-dichloro-N-((1-(propylsulfonyl)-4-((tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Glyt2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed