Compile Data Set for Download or QSAR
Found 35 Enz. Inhib. hit(s) with all data for entry = 50028308
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249737(2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249738(2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cells assessed as inhibition of ne...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249867(3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249738(2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257895(4,4-bis(4-fluorophenyl)-2-(3-nitrophenyl)-4,5-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258089(4-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257839(2-(3-bromophenyl)-4,4-bis(4-fluorophenyl)-4,5-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257835(2-(3-chlorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dih...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257837(4,4-bis(4-fluorophenyl)-2-(3-(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258039(3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258138(6-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257897(3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257896(4,4-bis(4-fluorophenyl)-2-(3-(methylsulfonyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257894(2-(3-fluorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dih...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258088(5-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257946(4,4-bis(4-fluorophenyl)-2-m-tolyl-4,5-dihydro-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257787(4,4-bis(4-fluorophenyl)-2-phenyl-4,5-dihydro-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258087(6-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257944(1-(3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imida...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258041(5-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257948(4,4-bis(4-fluorophenyl)-2-(3-methoxyphenyl)-4,5-di...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257990(4,4-bis(4-fluorophenyl)-2-(thiophen-2-yl)-4,5-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257786(2,4,4-triphenylimidazoline | CHEMBL493970)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257947((3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257989(4,4-bis(4-fluorophenyl)-2-(thiophen-3-yl)-4,5-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257836(2-(4-chlorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dih...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258040(4-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257991(2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257838(4,4-bis(4-fluorophenyl)-2-(4-(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257945(CHEMBL493997 | methyl 3-(4,4-bis(4-fluorophenyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257987(3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258042(2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258086(3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257788(2-(2-chlorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dih...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50257988(3-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24749RCPubMed