Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with all data for entry = 50028340
TargetCytochrome P450 1A2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50257964(5-fluoro-4-((R)-1-(3-fluorophenyl)propan-2-yloxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22807G5PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50257964(5-fluoro-4-((R)-1-(3-fluorophenyl)propan-2-yloxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22807G5PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50257963(2-(3-chlorobenzyloxy)-6-(piperazin-1-yl)pyrazine |...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22807G5PubMed