Compile Data Set for Download or QSAR
Found 14 Enz. Inhib. hit(s) with all data for entry = 50029027
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280813(5-[(1S,2S)-1-Hydroxy-2-(4-phenyl-piperidin-1-yl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50007677((+)-threo 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Tested for the Alpha-1 adrenergic receptor affinity in a standard radioligand binding assay with [3H]- prazosinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280811(5-[(1R,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Tested for the Alpha-1 adrenergic receptor affinity in a standard radioligand binding assay with [3H]- prazosinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280812(5-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280810(5-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-1-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 183nMAssay Description:Tested for the Alpha-1 adrenergic receptor affinity in a standard radioligand binding assay with [3H]- prazosinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280811(5-[(1R,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 231nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 263nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280813(5-[(1S,2S)-1-Hydroxy-2-(4-phenyl-piperidin-1-yl)-p...)copy SMILEScopy InChI
Affinity DataIC50: 349nMAssay Description:Tested for the Alpha-1 adrenergic receptor affinity in a standard radioligand binding assay with [3H]- prazosinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280810(5-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-1-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280812(5-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Tested for the Alpha-1 adrenergic receptor affinity in a standard radioligand binding assay with [3H]- prazosinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50079387(1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperid...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Tested for the Alpha-1 adrenergic receptor affinity in a standard radioligand binding assay with [3H]- prazosinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50007677((+)-threo 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 843nMAssay Description:Tested for the Alpha-1 adrenergic receptor affinity in a standard radioligand binding assay with [3H]- prazosinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50079387(1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperid...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5N4S