Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with all data for entry = 50030199
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50412085(CHEMBL455056)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081GHPubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50378060(CUCURBITACIN B)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081GHPubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50412087(CUCURBITACIN I | NSC-521777)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081GHPubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50412086(CHEMBL492404)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081GHPubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292421(CHEMBL480111 | Cucurbitacin L)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081GHPubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50292420(CHEMBL480112 | Cucurbitacin R)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of LFA1 expressed in human JY cells interaction with ICAM1-IG expressed in human HeLa cell monolayer after 45 mins by cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081GHPubMed