Compile Data Set for Download or QSAR
Found 39 Enz. Inhib. hit(s) with all data for entry = 50030371
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295231((+)-8'-methyl-11'-(2-(trifluoromethyl)phenyl)-4',5...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295231((+)-8'-methyl-11'-(2-(trifluoromethyl)phenyl)-4',5...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295222(10-butyl-11-(2-chloro-6-fluorophenyl)-3,3,8-trimet...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295254(11-(2-chloro-6-fluorophenyl)-3,3,8,10-tetramethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295221(11-(2-chloro-6-fluorophenyl)-10-ethyl-3,3,8-trimet...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295245(3,3,8-trimethyl-11-(2-(methylthio)phenyl)-2,3,4,5,...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295232(11'-(2-chlorophenyl)-8'-methyl-4',5',10',11'-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295246(3,3,8-trimethyl-11-(2-(trifluoromethyl)phenyl)-2,3...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295233(8'-methyl-11'-(2-(methylthio)phenyl)-4',5',10',11'...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295223(11'-(2-chloro-6-fluorophenyl)-8'-methyl-4',5',10',...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295247(11-(2-chlorophenyl)-3,3,8-trimethyl-2,3,4,5,10,11-...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295236(11-(2-chloro-6-fluorophenyl)-3,3,8-trimethyl-2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295237(11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-8-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295224(11-(2-chloro-6-fluorophenyl)-3,8-dimethyl-2,3,4,5,...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295234(11'-(2-fluoro-6-(trifluoromethyl)phenyl)-8'-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295248(3,3,8-trimethyl-11-(2-nitrophenyl)-2,3,4,5,10,11-h...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295231((+)-8'-methyl-11'-(2-(trifluoromethyl)phenyl)-4',5...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Antagonist activity at human neuromedin B receptor transfected in HEK293 cells assessed as inhibition of 1 nM neuromedin B-induced myo-[3H]inositol p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295235(8'-methyl-11'-(2-(trifluoromethylthio)phenyl)-4',5...)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295225(11-(2-chloro-6-fluorophenyl)-3-isopropyl-8-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295238(8-chloro-11-(2-chloro-6-fluorophenyl)-3,3-dimethyl...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295249(11-(2-methoxyphenyl)-3,3,8-trimethyl-2,3,4,5,10,11...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295240(11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-1-oxo-2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295250(11-(2-fluorophenyl)-3,3,8-trimethyl-2,3,4,5,10,11-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295239(11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-8-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295226(11-(2-chloro-6-fluorophenyl)-8-methyl-2,3,4,5,10,1...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295227(11-(2-chloro-6-fluorophenyl)-3-(4-methoxyphenyl)-8...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295241(11-(2-chloro-6-fluorophenyl)-8-methoxy-3,3-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295251(11-(2,6-difluorophenyl)-3,3,8-trimethyl-2,3,4,5,10...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295228(11-(2-chloro-6-fluorophenyl)-3-(furan-2-yl)-8-meth...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295229(11-(2-chloro-6-fluorophenyl)-3-(4-(dimethylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295236(11-(2-chloro-6-fluorophenyl)-3,3,8-trimethyl-2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Antagonist activity at human neuromedin B receptor transfected in HEK293 cells assessed as inhibition of 1 nM neuromedin B-induced myo-[3H]inositol p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295252(3,3,8-trimethyl-11-phenyl-2,3,4,5,10,11-hexahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295243(11-(2-chloro-6-fluorophenyl)-8-hydroxy-3,3-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295242(11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-1-oxo-2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295236(11-(2-chloro-6-fluorophenyl)-3,3,8-trimethyl-2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition gastrin-releasing peptide receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295231((+)-8'-methyl-11'-(2-(trifluoromethyl)phenyl)-4',5...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295230(10-(2-chloro-6-fluorophenyl)-7-methyl-2,3,9,10-tet...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295253(11-(2-chloro-6-fluorophenyl)-3,3,5,8-tetramethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50295244(11-(2-chloro-6-fluorophenyl)-3,3-dimethyl-1-oxo-2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WG8PubMed