Compile Data Set for Download or QSAR
Found 61 Enz. Inhib. hit(s) with all data for entry = 50030480
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Displacement of [3H]PGD2 from mouse CRTh2 receptor expressed in K562 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296849(2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296850(2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296847(2-(1-(4-cyano-3-ethoxyphenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296859(2-(2-methyl-1-(4-nitrophenylsulfonyl)-1H-pyrrolo[2...)copy SMILEScopy InChI
Affinity DataKi:  48nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296857(2-(1-(3,4-dichlorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  52nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296846(2-(1-(4-fluoro-3-methoxyphenylsulfonyl)-2-methyl-1...)copy SMILEScopy InChI
Affinity DataKi:  56nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50213919(2-(4-chloro-2-cycloheptylphenoxy)acetic acid | CHE...)copy SMILEScopy InChI
Affinity DataKi:  59nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161746((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...)copy SMILEScopy InChI
Affinity DataKi:  73nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296851(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi:  103nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296845(2-(1-(3-chloro-4-fluorophenylsulfonyl)-2-methyl-1H...)copy SMILEScopy InChI
Affinity DataKi:  158nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296854(2-(2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]py...)copy SMILEScopy InChI
Affinity DataKi:  282nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296852(2-(1-(3-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi:  377nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296856(2-(2-methyl-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataKi:  619nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296858(2-(1-(4-chloro-3-(trifluoromethyl)phenylsulfonyl)-...)copy SMILEScopy InChI
Affinity DataKi:  1.17E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296855(2-(1-(4-methoxyphenylsulfonyl)-2-methyl-1H-pyrrolo...)copy SMILEScopy InChI
Affinity DataKi:  2.62E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296853(2-(1-(2-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi:  3.22E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296851(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296851(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human thromboxane A2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296847(2-(1-(4-cyano-3-ethoxyphenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296849(2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296850(2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Antagonist activity against CRTh2 receptor in human whole blood assessed as eosinophil shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296846(2-(1-(4-fluoro-3-methoxyphenylsulfonyl)-2-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161746((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296847(2-(1-(4-cyano-3-ethoxyphenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296850(2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Antagonist activity against CRTh2 receptor in human whole blood assessed as eosinophil shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296849(2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296845(2-(1-(3-chloro-4-fluorophenylsulfonyl)-2-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296849(2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Antagonist activity against CRTh2 receptor in human whole blood assessed as eosinophil shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296846(2-(1-(4-fluoro-3-methoxyphenylsulfonyl)-2-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296850(2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296851(2-(1-(4-chlorophenylsulfonyl)-2-methyl-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296857(2-(1-(3,4-dichlorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50213919(2-(4-chloro-2-cycloheptylphenoxy)acetic acid | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 148nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296846(2-(1-(4-fluoro-3-methoxyphenylsulfonyl)-2-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Antagonist activity against CRTh2 receptor in human whole blood assessed as eosinophil shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 167nMAssay Description:Antagonist activity against mouse CRTh2 receptor expressed in K562 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161746((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 195nMAssay Description:Antagonist activity against CRTh2 receptor in human whole blood assessed as eosinophil shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50161746((R)-3-(3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50213919(2-(4-chloro-2-cycloheptylphenoxy)acetic acid | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 248nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296845(2-(1-(3-chloro-4-fluorophenylsulfonyl)-2-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 311nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296857(2-(1-(3,4-dichlorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 354nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296857(2-(1-(3,4-dichlorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 629nMAssay Description:Antagonist activity against CRTh2 receptor in human whole blood assessed as eosinophil shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of CCKalpha receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against prostaglandin E2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against prostaglandin E3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
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