Compile Data Set for Download or QSAR
Found 126 Enz. Inhib. hit(s) with all data for entry = 50030759
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300970(7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)-3-(py...)copy SMILEScopy InChI
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300964(CHEMBL584270 | rac-7-(6-methoxypyridin-3-yl)-1-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300953(3-[(trans-4-hydroxycyclohexyl)amino]-7-(6-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300972(7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)-3-(py...)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50296256(7-(6-methoxypyridin-3-yl)-3-(2-morpholinoethylamin...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300983(7-(6-methoxypyridin-3-yl)-3-(2-(4-methylpiperazin-...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300976(2-(7-(6-methoxypyridin-3-yl)-2-oxo-1-(2-propoxyeth...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300977(7-(6-methoxypyridin-3-yl)-3-(2-oxo-2-(pyrrolidin-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300989((S)-3-(2-hydroxypropylamino)-7-(6-methoxypyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300991((R)-3-(2-hydroxypropylamino)-7-(6-methoxypyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300962(3-(2-ethoxyethylamino)-7-(6-methoxypyridin-3-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300985(3-(2-(4-ethylpiperazin-1-yl)-2-oxoethylamino)-7-(6...)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300978(3-(2-(4-hydroxypiperidin-1-yl)-2-oxoethylamino)-7-...)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300963(7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)-3-((t...)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300948((R)-3-(1-hydroxypropan-2-ylamino)-7-(6-methoxypyri...)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300980(7-(6-methoxypyridin-3-yl)-3-(2-morpholino-2-oxoeth...)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300961(3-(2-ethoxyethylamino)-7-(6-methoxypyridin-3-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.170nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300950((S)-3-(1-hydroxypropan-2-ylamino)-7-(6-methoxypyri...)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300957(3-(2-aminoethylamino)-7-(6-methoxypyridin-3-yl)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300951((R)-3-(1-hydroxybutan-2-ylamino)-7-(6-methoxypyrid...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300987(3-(3-hydroxypropylamino)-7-(6-methoxypyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300971(7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)-3-(py...)copy SMILEScopy InChI
Affinity DataIC50: 0.280nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300952(3-(trans-4-hydroxycyclohexylamino)-7-(6-methoxypyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300982(7-(6-methoxypyridin-3-yl)-3-(2-(4-methylpiperazin-...)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50296257(7-(6-methoxypyridin-3-yl)-3-(2-morpholinoethylamin...)copy SMILEScopy InChI
Affinity DataIC50: 0.340nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300988((S)-3-(2-hydroxypropylamino)-7-(6-methoxypyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.340nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300969(7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)-3-(py...)copy SMILEScopy InChI
Affinity DataIC50: 0.360nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300984(3-(2-(4-ethylpiperazin-1-yl)-2-oxoethylamino)-7-(6...)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300975(2-(7-(6-methoxypyridin-3-yl)-2-oxo-1-(2-propoxyeth...)copy SMILEScopy InChI
Affinity DataIC50: 0.430nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300990((R)-3-(2-hydroxypropylamino)-7-(6-methoxypyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.540nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300949((S)-3-(1-hydroxypropan-2-ylamino)-7-(6-methoxypyri...)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300968(2-(7-(6-methoxypyridin-3-yl)-2-oxo-1-(2-propoxyeth...)copy SMILEScopy InChI
Affinity DataIC50: 0.680nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300974(2-(7-(6-methoxypyridin-3-yl)-2-oxo-1-(2-propoxyeth...)copy SMILEScopy InChI
Affinity DataIC50: 0.680nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300986(3-(3-hydroxypropylamino)-7-(6-methoxypyridin-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.710nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300955(3-(2-(dimethylamino)ethylamino)-7-(6-methoxypyridi...)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300947((R)-3-(1-hydroxypropan-2-ylamino)-7-(6-methoxypyri...)copy SMILEScopy InChI
Affinity DataIC50: 0.880nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300960(3-(2-hydroxyethylamino)-7-(6-methoxypyridin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300958(3-(2-(2-hydroxyethylamino)ethylamino)-7-(6-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300966(2-(7-(6-methoxypyridin-3-yl)-2-oxo-1-(2-propoxyeth...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300979(7-(6-methoxypyridin-3-yl)-3-(2-morpholino-2-oxoeth...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300959(3-(2-hydroxyethylamino)-7-(6-methoxypyridin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300981(7-(6-methoxypyridin-3-yl)-3-(2-oxo-2-(piperazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300967(2-(7-(6-methoxypyridin-3-yl)-2-oxo-1-(2-propoxyeth...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300973(2-(7-(6-methoxypyridin-3-yl)-2-oxo-1-(2-propoxyeth...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300965(2-(7-(6-methoxypyridin-3-yl)-2-oxo-1-(2-propoxyeth...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300954(3-(2-(dimethylamino)ethylamino)-7-(6-methoxypyridi...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300972(7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)-3-(py...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300964(CHEMBL584270 | rac-7-(6-methoxypyridin-3-yl)-1-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300962(3-(2-ethoxyethylamino)-7-(6-methoxypyridin-3-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50300953(3-[(trans-4-hydroxycyclohexyl)amino]-7-(6-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Inhibition of PDE6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41RHVPubMed
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