TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 69nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 85nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 95nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 290nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 330nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 360nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 390nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 410nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 450nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 460nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 540nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 540nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 550nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 590nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 620nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 660nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 690nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 690nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 720nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 720nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 810nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 930nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 940nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 960nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair