Compile Data Set for Download or QSAR
Found 32 Enz. Inhib. hit(s) with all data for entry = 50031510
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313664(CHEMBL1077218 | N-(6-chloro-5-(furan-3-yl)-1H-inda...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313678(CHEMBL1093747 | N-(5-bromo-6-(4-hydroxyphenyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313663(CHEMBL1095366 | N-(6-chloro-5-(4-hydroxyphenyl)-1H...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313668(CHEMBL1091082 | N-(6-chloro-5-(4-fluorophenyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50314525(1-(6-chloro-5-phenyl-1H-indazol-3-yl)-3-phenylurea...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of GSK3beta assessed as tau phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313656(CHEMBL1086174 | N-(6-phenyl-1H-indazol-3-yl)butyra...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313700(CHEMBL1089722 | N-(5-bromo-6-chloro-1H-indazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313668(CHEMBL1091082 | N-(6-chloro-5-(4-fluorophenyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313662(CHEMBL1095041 | N-(5-(4-aminophenyl)-6-chloro-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 980nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313686(CHEMBL1085918 | N-(6-(pyridin-3-yl)-1H-indazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313666(CHEMBL1097694 | N-(6-chloro-5-p-tolyl-1H-indazol-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313653(CHEMBL1083208 | N-(6-(thiophen-3-yl)-1H-indazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313659(CHEMBL1095038 | N-(6-(3,5-difluorophenyl)-1H-indaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313667(CHEMBL1091081 | N-(6-chloro-5-(4-nitrophenyl)-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 4.46E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313686(CHEMBL1085918 | N-(6-(pyridin-3-yl)-1H-indazol-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313678(CHEMBL1093747 | N-(5-bromo-6-(4-hydroxyphenyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313678(CHEMBL1093747 | N-(5-bromo-6-(4-hydroxyphenyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313656(CHEMBL1086174 | N-(6-phenyl-1H-indazol-3-yl)butyra...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313678(CHEMBL1093747 | N-(5-bromo-6-(4-hydroxyphenyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313678(CHEMBL1093747 | N-(5-bromo-6-(4-hydroxyphenyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313669(CHEMBL1091083 | N-(5-(4-(benzyloxy)phenyl)-6-chlor...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313678(CHEMBL1093747 | N-(5-bromo-6-(4-hydroxyphenyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50314525(1-(6-chloro-5-phenyl-1H-indazol-3-yl)-3-phenylurea...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313659(CHEMBL1095038 | N-(6-(3,5-difluorophenyl)-1H-indaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313698(CHEMBL1082237 | N-(6-(4-hydroxyphenyl)-1H-indazol-...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313701(4-(6-chloro-1H-indazol-3-ylamino)-4-oxobutanoic ac...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Sanofi-aventis

Curated by ChEMBL
LigandPNGBDBM50313698(CHEMBL1082237 | N-(6-(4-hydroxyphenyl)-1H-indazol-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45WFPubMed