Compile Data Set for Download or QSAR
Found 36 Enz. Inhib. hit(s) with all data for entry = 50031981
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322727(4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322725(3-[(3-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322724(3-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322728(4-[(3-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322707(6-amino-4-(4-(dimethylamino)phenyl)-3-(4-isobutylp...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322708(4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322706(3-(4-chlorobenzyl)-5-(3-methoxy-4-(pyridin-4-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322705(3-benzyl-5-((1,3-dimethyl-2-oxo-2,3-dihydro-1H-ben...)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322709(4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)me...)copy SMILEScopy InChI
Affinity DataIC50: 161nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322710(4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)me...)copy SMILEScopy InChI
Affinity DataIC50: 248nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322704(CHEMBL1173377 | N-(3-chlorophenyl)-2-(6-(1,3-dioxo...)copy SMILEScopy InChI
Affinity DataIC50: 261nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50148348((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)copy SMILEScopy InChI
Affinity DataIC50: 442nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322703(4-((2-methoxy-4-((3-(4-nitrobenzyl)-2,4-dioxothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 442nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322715(5-(4-(benzyloxy)benzylidene)-3-(4-fluorobenzyl)thi...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322699(3-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322701(4-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322700(3-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-...)copy SMILEScopy InChI
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322708(4-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322716(3-benzyl-5-(4-(benzyloxy)benzylidene)thiazolidine-...)copy SMILEScopy InChI
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322723(CHEMBL1173235 | methyl4-((4-((3-benzyl-2,4-dioxoth...)copy SMILEScopy InChI
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322710(4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)me...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322703(4-((2-methoxy-4-((3-(4-nitrobenzyl)-2,4-dioxothiaz...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322726(2-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322729(2-[(3-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322718(5-(4-(benzyloxy)-3-methoxybenzylidene)-3-(4-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 5.87E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322702(4-((4-((3-(4-tert-butylbenzyl)-2,4-dioxothiazolidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322702(4-((4-((3-(4-tert-butylbenzyl)-2,4-dioxothiazolidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322721(CHEMBL1172970 | methyl4-((2-methoxy-4-((3-(4-nitro...)copy SMILEScopy InChI
Affinity DataIC50: 6.09E+4nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322712(3-benzyl-5-benzylidenethiazolidine-2,4-dione | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322711(5-benzylidene-3-(4-fluorobenzyl)thiazolidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322720(CHEMBL1172921 | methyl4-((4-((3-(4-tert-butylbenzy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322713(5-(4-(benzyloxy)benzylidene)-3-(4-tert-butylbenzyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322722(CHEMBL1172969 | methy4-((4-((3-(4-fluorobenzyl)-2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322717(5-(4-(benzyloxy)-3-methoxybenzylidene)-3-(4-nitrob...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322719(3-benzyl-5-(4-(benzyloxy)-3-methoxybenzylidene)thi...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50322714(5-(4-(benzyloxy)benzylidene)-3-(4-nitrobenzyl)thia...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DXKPubMed