Compile Data Set for Download or QSAR
Found 25 Enz. Inhib. hit(s) with all data for entry = 50031986
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322822((S)-N-(3-(4-(2-hydroxy-1-phenylethylamino)-6-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of GST-tagged EGFR expressed in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-tagged EGFR expressed in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of GST-tagged EGFR expressed in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322816(1-{4-[2-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamin...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322821((S)-N-(4-(4-(2-hydroxy-1-phenylethylamino)-6-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of GST-tagged EGFR expressed in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322820(CHEMBL1172781 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 223nMAssay Description:Inhibition of GST-tagged EGFR expressed in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322805((5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)-[2-(1H-imi...)copy SMILEScopy InChI
Affinity DataIC50: 296nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322817(CHEMBL1173801 | N-{4-[2-(5,6-Diphenylfuro[2,3-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 304nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM14800(2-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-et...)copy SMILEScopy InChI
Affinity DataIC50: 309nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322812(4-(3,5-Dimethylpiperazin-1-yl)-5,6-diphenylfuro[2,...)copy SMILEScopy InChI
Affinity DataIC50: 334nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322810((5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)-(2-pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 535nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322807(CHEMBL1173151 | [2-(4-Aminophenyl)ethyl]-(5,6-diph...)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322813(4-[2-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamino)e...)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322809(2-[2-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamino)e...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322808(CHEMBL1173152 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 792nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322806(3-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamino)prop...)copy SMILEScopy InChI
Affinity DataIC50: 796nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322803(1-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 807nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322811((2,5-Dimethoxy-2,5-dihydrofuran-2-ylmethyl)-(5,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 827nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322815((4-Aminobenzyl)-(5,6-diphenylfuro[2,3-d]pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 945nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322814(1-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamino)prop...)copy SMILEScopy InChI
Affinity DataIC50: 973nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322804((5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)-(2-morphol...)copy SMILEScopy InChI
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322802((5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)-(3-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322818(CHEMBL1173465 | N-{4-[2-(5,6-Diphenylfuro[2,3-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 5.83E+3nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322819(3-(5,6-diphenylfuro[2,3-d]pyrimidin-4-ylamino)-N-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora AChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60P87PubMed