Compile Data Set for Download or QSAR
Found 31 Enz. Inhib. hit(s) with all data for entry = 50031992
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322858((R)-3-phenyl-N-((R)-6-(3-(pyrrolidin-1-yl)prop-1-e...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322857((R)-3-phenyl-N-((R)-6-(3-(piperidin-1-yl)prop-1-en...)copy SMILEScopy InChI
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322868((R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1...)copy SMILEScopy InChI
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322859((R)-N-((R)-6-(3-((S)-3-hydroxypyrrolidin-1-yl)prop...)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322867((R)-N-((R)-6-(3-(isopropylamino)prop-1-en-2-yl)-1,...)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322866((R)-N-((R)-6-(3-(tert-butylamino)prop-1-en-2-yl)-1...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322861((R)-N-((R)-6-(3-(azetidin-1-yl)prop-1-en-2-yl)-1,2...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322860((R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322856((R)-3-phenyl-N-((R)-6-(1-(piperidin-1-ylmethyl)cyc...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322865((R)-N-((R)-6-(3-(cyclopropylmethylamino)prop-1-en-...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322863((R)-N-((R)-6-(3-(2-hydroxyethylamino)prop-1-en-2-y...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322869((R)-N-((R)-6-(3-(cyclopentylamino)prop-1-en-2-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322855((3R)-3-phenyl-N-((1R)-6-(1-(piperidin-1-yl)propan-...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322864((R)-N-((R)-6-(3-(2-methoxyethylamino)prop-1-en-2-y...)copy SMILEScopy InChI
Affinity DataKi:  42nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322862((R)-N-((R)-6-(3-(dimethylamino)prop-1-en-2-yl)-1,2...)copy SMILEScopy InChI
Affinity DataKi:  78nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322870((R)-3-(4-fluorophenyl)-N-((R)-6-(3-(pyrrolidin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322859((R)-N-((R)-6-(3-((S)-3-hydroxypyrrolidin-1-yl)prop...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322858((R)-3-phenyl-N-((R)-6-(3-(pyrrolidin-1-yl)prop-1-e...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322860((R)-N-((R)-6-(3-((R)-3-hydroxypyrrolidin-1-yl)prop...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322864((R)-N-((R)-6-(3-(2-methoxyethylamino)prop-1-en-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322863((R)-N-((R)-6-(3-(2-hydroxyethylamino)prop-1-en-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322857((R)-3-phenyl-N-((R)-6-(3-(piperidin-1-yl)prop-1-en...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322867((R)-N-((R)-6-(3-(isopropylamino)prop-1-en-2-yl)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322868((R)-N-((R)-6-(3-(cyclobutylamino)prop-1-en-2-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322869((R)-N-((R)-6-(3-(cyclopentylamino)prop-1-en-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322866((R)-N-((R)-6-(3-(tert-butylamino)prop-1-en-2-yl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322856((R)-3-phenyl-N-((R)-6-(1-(piperidin-1-ylmethyl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322865((R)-N-((R)-6-(3-(cyclopropylmethylamino)prop-1-en-...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322862((R)-N-((R)-6-(3-(dimethylamino)prop-1-en-2-yl)-1,2...)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322861((R)-N-((R)-6-(3-(azetidin-1-yl)prop-1-en-2-yl)-1,2...)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50322855((3R)-3-phenyl-N-((1R)-6-(1-(piperidin-1-yl)propan-...)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W88PubMed