Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with all data for entry = 50032051
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50323721((3S,6S,9S,12R,15S,18S,21S,24S,27S,30S,33S)-27-(2-(...)copy SMILEScopy InChI
Affinity DataKi:  1.84nMAssay Description:Inhibition of calcineurin phosphatase activity of CyPAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataKi:  2.64nMAssay Description:Inhibition of calcineurin phosphatase activity of CyPAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human recombinant CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant CYP2C19 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50323721((3S,6S,9S,12R,15S,18S,21S,24S,27S,30S,33S)-27-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human recombinant CYP2C19 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50323721((3S,6S,9S,12R,15S,18S,21S,24S,27S,30S,33S)-27-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of human recombinant CYP2C9 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataIC50: 3.88E+4nMAssay Description:Inhibition of human recombinant CYP2C9 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50323721((3S,6S,9S,12R,15S,18S,21S,24S,27S,30S,33S)-27-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 5.85E+4nMAssay Description:Inhibition of human recombinant CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50323721((3S,6S,9S,12R,15S,18S,21S,24S,27S,30S,33S)-27-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP1A2 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP1A2 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP2D6 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Scynexis, Inc.

Curated by ChEMBL
LigandPNGBDBM50323721((3S,6S,9S,12R,15S,18S,21S,24S,27S,30S,33S)-27-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CYP2D6 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40VDGPubMed