Compile Data Set for Download or QSAR
Found 50 Enz. Inhib. hit(s) with all data for entry = 50032165
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325241(CHEMBL1223114)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325237((5S,8S,11S)-11-(2-(3,3-diphenylpropanoyloxy)acetyl...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325238((5S,8S,11S)-11-(2-(2-benzyl-3-phenylpropanoyloxy)a...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325240(CHEMBL1223113)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325236((5S,8S,11S)-5-isopropyl-8-methyl-11-(2-(2-(naphtha...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325239(CHEMBL1223112)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM12197((3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-(4-hydr...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325235((5S,8S,11S)-5-isopropyl-8-methyl-3,6,9-trioxo-1-ph...)copy SMILEScopy InChI
Affinity DataKi:  134nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325250((S)-3-(benzyloxycarbonylamino)-5-(2-(naphthalen-1-...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325259((S)-5-(2-(1H-indol-3-yl)acetoxy)-3-(benzyloxycarbo...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325260((S)-5-(2-(benzofuran-3-yl)acetoxy)-3-(benzyloxycar...)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325257((S)-3-(benzyloxycarbonylamino)-5-(3,3-diphenylprop...)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325252((3S)-3-(benzyloxycarbonylamino)-5-(2-(naphthalen-1...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325251((S)-3-(benzyloxycarbonylamino)-5-(2-(naphthalen-1-...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325258((3S)-3-(benzyloxycarbonylamino)-4-oxo-5-(3-phenyl-...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325246((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(2-(phenylt...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325261((S)-5-(2-(benzo[b]thiophen-3-yl)acetoxy)-3-(benzyl...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325254((S)-3-(benzyloxycarbonylamino)-5-(2-(4-methylnapht...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325249((S)-3-(benzyloxycarbonylamino)-5-(2-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325234(CHEMBL1223107)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325245((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(2-phenoxya...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325255((S)-3-(benzyloxycarbonylamino)-5-(2-(5-methylnapht...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325262((S)-5-(2-(benzo[d]thiazol-4-yl)acetoxy)-3-(benzylo...)copy SMILEScopy InChI
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325253((S)-3-(benzyloxycarbonylamino)-5-(2-(2-methylnapht...)copy SMILEScopy InChI
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50071541((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(3-phenylpr...)copy SMILEScopy InChI
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325247((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(2-(phenyla...)copy SMILEScopy InChI
Affinity DataKi:  5.60E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325248((S)-3-(benzyloxycarbonylamino)-5-(3-(naphthalen-2-...)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325267((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(2-oxoindol...)copy SMILEScopy InChI
Affinity DataKi:  6.77E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325243((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(2-phenylac...)copy SMILEScopy InChI
Affinity DataKi:  8.30E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325256((S)-3-(benzyloxycarbonylamino)-5-(2-(8-methylnapht...)copy SMILEScopy InChI
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325265((S)-3-(benzyloxycarbonylamino)-4-oxo-5-((3aS,7aS)-...)copy SMILEScopy InChI
Affinity DataKi:  9.20E+3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325268((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(1-oxoisoin...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325263((S)-3-(benzyloxycarbonylamino)-5-((3aS,7R,7aR)-7-(...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325244((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(4-phenylbu...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325266((S)-3-(benzyloxycarbonylamino)-4-oxo-5-((3aS,7aR)-...)copy SMILEScopy InChI
Affinity DataKi:  1.75E+4nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325269((S)-5-(benzamidooxy)-3-(benzyloxycarbonylamino)-4-...)copy SMILEScopy InChI
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325271((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(3-phenylpr...)copy SMILEScopy InChI
Affinity DataKi:  2.75E+4nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325270((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(2-phenylac...)copy SMILEScopy InChI
Affinity DataKi:  6.65E+4nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325272((S)-3-(benzyloxycarbonylamino)-5-(2-(naphthalen-1-...)copy SMILEScopy InChI
Affinity DataKi:  8.40E+4nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325264((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(2-oxopyrro...)copy SMILEScopy InChI
Affinity DataKi:  8.72E+4nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325242((S)-3-(benzyloxycarbonylamino)-4-oxo-5-(5-phenylpe...)copy SMILEScopy InChI
Affinity DataKi:  1.19E+5nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325273((S)-3-(benzyloxycarbonylamino)-5-(3-(naphthalen-1-...)copy SMILEScopy InChI
Affinity DataKi:  2.98E+5nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325236((5S,8S,11S)-5-isopropyl-8-methyl-11-(2-(2-(naphtha...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325238((5S,8S,11S)-11-(2-(2-benzyl-3-phenylpropanoyloxy)a...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325240(CHEMBL1223113)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325241(CHEMBL1223114)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325237((5S,8S,11S)-11-(2-(3,3-diphenylpropanoyloxy)acetyl...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325239(CHEMBL1223112)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM12197((3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-(4-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed
TargetCaspase-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50325235((5S,8S,11S)-5-isopropyl-8-methyl-3,6,9-trioxo-1-ph...)copy SMILEScopy InChI
Affinity DataIC50: 976nMAssay Description:Inhibition of ICEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ90K1PubMed