Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with all data for entry = 50032270
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326519((E)-N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-...)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326514((E)-4-(Methylamino)-but-2-enoic acid [4-(3-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326513((E)-4-Methylamino-but-2-enoicacid[4-(3-chloro-4-fl...)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326517((E)-4-[(4-Fluorobenzyl)methylamino]-but-2-enoic ac...)copy SMILEScopy InChI
Affinity DataIC50: 0.570nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326518((E)-4-[(2-Fluoroethyl)methylamino]-but-2-enoic aci...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM3303(4-Anilinoquinazoline deriv. 54 | 4-N-(3-bromopheny...)copy SMILEScopy InChI
Affinity DataIC50: 0.810nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326516((E)-4-{[1-(2-Fluoroethyl)-1H-[1,2,3]triazol-4-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 1.81nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326515((E)-N-[4-(3-Chloro-4-fluorophenylamino)-3-cyano-7-...)copy SMILEScopy InChI
Affinity DataIC50: 4.05nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326514((E)-4-(Methylamino)-but-2-enoic acid [4-(3-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 5.35nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)copy SMILEScopy InChI
Affinity DataIC50: 8.02nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326513((E)-4-Methylamino-but-2-enoicacid[4-(3-chloro-4-fl...)copy SMILEScopy InChI
Affinity DataIC50: 8.12nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326517((E)-4-[(4-Fluorobenzyl)methylamino]-but-2-enoic ac...)copy SMILEScopy InChI
Affinity DataIC50: 16.5nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326516((E)-4-{[1-(2-Fluoroethyl)-1H-[1,2,3]triazol-4-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 22.0nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326518((E)-4-[(2-Fluoroethyl)methylamino]-but-2-enoic aci...)copy SMILEScopy InChI
Affinity DataIC50: 23.0nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326519((E)-N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-...)copy SMILEScopy InChI
Affinity DataIC50: 60.2nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM3303(4-Anilinoquinazoline deriv. 54 | 4-N-(3-bromopheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50326515((E)-N-[4-(3-Chloro-4-fluorophenylamino)-3-cyano-7-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7GG2PubMed