Compile Data Set for Download or QSAR
Found 141 Enz. Inhib. hit(s) with all data for entry = 50032333
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50130561((R)-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dime...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327257(3-(1-(cyclopropylmethyl)piperidin-4-yloxy)-N-(3-(3...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325855(CHEMBL1223951 | exo-3-((1R,3s,5S)-8-benzyl-8-azabi...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327259(3-(1-benzylpiperidin-4-yloxy)benzamide | CHEMBL125...)copy SMILEScopy InChI
Affinity DataKi:  75nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327258(3-(1-(cyclopropylmethyl)piperidin-4-yloxy)benzamid...)copy SMILEScopy InChI
Affinity DataKi:  146nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327248(CHEMBL1257821 | endo-3-(8-(4-methylbenzyl)-8-azabi...)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327247(CHEMBL1257820 | endo-3-(8-(3-phenylpropyl)-8-azabi...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327244(3-Endo-(8-((5-methylthiophen-2-yl)methyl)-8-azabic...)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327246(CHEMBL1257698 | endo-3-(8-phenethyl-8-azabicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327243(CHEMBL1257577 | endo-3-(8-(thiophen-2-ylmethyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 0.430nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50130561((R)-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dime...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327249(CHEMBL1257937 | endo-3-(8-(3-methylbenzyl)-8-azabi...)copy SMILEScopy InChI
Affinity DataIC50: 0.520nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325855(CHEMBL1223951 | exo-3-((1R,3s,5S)-8-benzyl-8-azabi...)copy SMILEScopy InChI
Affinity DataIC50: 0.610nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327250(CHEMBL1257938 | endo-3-(8-(2-methylbenzyl)-8-azabi...)copy SMILEScopy InChI
Affinity DataIC50: 0.620nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327256(CHEMBL1258280 | endo-3-(8-(benzo[d][1,3]dioxol-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 0.620nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327264(CHEMBL1258503 | endo-3-(8-(2-oxo-2-(phenylamino)et...)copy SMILEScopy InChI
Affinity DataIC50: 0.720nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327268(CHEMBL1258725 | endo-3-(8-(1,2,3,4-tetrahydronapht...)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327251(CHEMBL1258047 | endo-3-(8-(pyridin-4-ylmethyl)-8-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327266(CHEMBL1258616 | endo-3-(8-(1-(5-methylthiophen-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327274(CHEMBL1257227 | endo-3-(8-((S)-1-phenylethyl)-8-az...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327253(CHEMBL1258164 | endo-3-(8-(pyridin-2-ylmethyl)-8-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327255(CHEMBL1258279 | endo-3-(8-(cyclohexylmethyl)-8-aza...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327245(CHEMBL1255595 | endo-3-(8-((5-methylfuran-2-yl)met...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327275(CHEMBL1257347 | endo-3-(8-((R)-1-(5-methylthiophen...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327277(CHEMBL1257458 | endo-3-(8-((R)-1-(6-methylpyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327279(CHEMBL1257579 | endo-3-(8-((R)-1-(6-chloropyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327252(CHEMBL1258048 | endo-3-(8-(pyridin-3-ylmethyl)-8-a...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327272(CHEMBL1258962 | endo-3-(8-(1-(pyridin-4-yl)ethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327276(CHEMBL1257348 | endo-3-(8-((R)-1-(3-methoxyphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327270(CHEMBL1258846 | endo-3-(8-(2-phenylpropan-2-yl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327271(CHEMBL1258961 | endo-3-(8-(1-phenylcyclopropyl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327267(CHEMBL1258724 | endo-3-(8-(1-o-tolylethyl)-8-azabi...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327265(CHEMBL1258615 | endo-3-(8-(1-phenylethyl)-8-azabic...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327261(CHEMBL1258391 | endo-3-(8-(4-(methylsulfonylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327254(CHEMBL1258166 | endo-3-(8-(cyclopropylmethyl)-8-az...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327256(CHEMBL1258280 | endo-3-(8-(benzo[d][1,3]dioxol-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327273(CHEMBL1257226 | endo-3-(8-((R)-1-phenylethyl)-8-az...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327278(CHEMBL1257459 | endo-3-(8-((R)-1-(2-chloropyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327269(CHEMBL1258845 | endo-3-(8-cyclohexyl-8-azabicyclo[...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327244(3-Endo-(8-((5-methylthiophen-2-yl)methyl)-8-azabic...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human delta opioid receptor assessed as inhibition of SNC80-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327263(CHEMBL1258502 | endo-3-(8-(2-oxo-2-(pyrrolidin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327262(CHEMBL1258392 | endo-3-(8-((1-methyl-1H-pyrazol-4-...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327260(CHEMBL1258165 | endo-3-(8-methyl-8-azabicyclo[3.2....)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327261(CHEMBL1258391 | endo-3-(8-(4-(methylsulfonylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50130561((R)-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dime...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human mu opioid receptor assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327276(CHEMBL1257348 | endo-3-(8-((R)-1-(3-methoxyphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50327248(CHEMBL1257821 | endo-3-(8-(4-methylbenzyl)-8-azabi...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Antagonist activity at human kappa opioid receptor assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4PV1PubMed
Displayed 1 to 50 (of 141 total ) | Next | Last >>
Jump to: