Compile Data Set for Download or QSAR
Found 33 Enz. Inhib. hit(s) with all data for entry = 50032732
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50333880(CHEMBL1614664 | Hypericin | Pseudohypericin)copy SMILEScopy InChI
Affinity DataKi:  1.90E+3nMAssay Description:Mixed-type inhibition of rat liver cytosolic TrxR1 by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50333880(CHEMBL1614664 | Hypericin | Pseudohypericin)copy SMILEScopy InChI
Affinity DataKi:  8.10E+3nMAssay Description:Mixed-type inhibition of rat liver cytosolic TrxR1 at protein-substrate complex by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetGlutathione reductase(Saccharomyces cerevisiae)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50333880(CHEMBL1614664 | Hypericin | Pseudohypericin)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of yeast glutathione reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetGlutathione reductase(Saccharomyces cerevisiae)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50060874(1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[...)copy SMILEScopy InChI
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of yeast glutathione reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50333880(CHEMBL1614664 | Hypericin | Pseudohypericin)copy SMILEScopy InChI
Affinity DataIC50: 4.41E+3nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50333880(CHEMBL1614664 | Hypericin | Pseudohypericin)copy SMILEScopy InChI
Affinity DataIC50: 7.45E+3nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50333880(CHEMBL1614664 | Hypericin | Pseudohypericin)copy SMILEScopy InChI
Affinity DataIC50: 7.45E+3nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50060874(1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50060874(1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM32021(4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM32021(4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50005886(1,8-Dihydroxy-3-methoxy-6-methylanthraquinone | 1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50085551(1,8-Dihydroxy-3-hydroxymethyl-anthraquinone | 1,8-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50455992(CHEBI:3687 | Chrysophanol)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50005886(1,8-Dihydroxy-3-methoxy-6-methylanthraquinone | 1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50455992(CHEBI:3687 | Chrysophanol)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50060874(1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[...)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50060874(1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[...)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-Dihydroxyanthrachinon | 1,4-dihydroxy-9,10-ant...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50060860(9(10H)-anthracenone | 9,10-dihydro-9-oxoanthracene...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50085551(1,8-Dihydroxy-3-hydroxymethyl-anthraquinone | 1,8-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50269016(CHEMBL497001 | aloin)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM80739(MLS002473001 | SMR001397106 | cid_91440 | sennosid...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50333879(CHEMBL1644068 | Skyrin glucoside)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50333878(CHEMBL1172006 | Frangulin A)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50333879(CHEMBL1644068 | Skyrin glucoside)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50333878(CHEMBL1172006 | Frangulin A)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50269016(CHEMBL497001 | aloin)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM11316(1,8-dihydroxy-9,10-dihydroanthracene-9,10-dione | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-Dihydroxyanthrachinon | 1,4-dihydroxy-9,10-ant...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50060860(9(10H)-anthracenone | 9,10-dihydro-9-oxoanthracene...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM80739(MLS002473001 | SMR001397106 | cid_91440 | sennosid...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed
TargetThioredoxin reductase 2, mitochondrial(Rattus norvegicus)
University of Padova

Curated by ChEMBL
LigandPNGBDBM11316(1,8-dihydroxy-9,10-dihydroanthracene-9,10-dione | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S4NPubMed