Compile Data Set for Download or QSAR
Found 23 Enz. Inhib. hit(s) with all data for entry = 50032752
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334181(2-(4-oxo-5-(4-phenoxybenzylidene)-2-thioxothiazoli...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334174(2-(2,4-dioxo-5-(3-phenoxybenzylidene)thiazolidin-3...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50149743((Z)-2-(5-(3-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334182(2-(5-(3-methoxybenzylidene)-4-oxo-2-thioxothiazoli...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50149769((Z)-2-(5-(4-(benzyloxy)benzylidene)-4-oxo-2-thioxo...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334176(2-(5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazolid...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334180(2-(4-oxo-5-(3-phenoxybenzylidene)-2-thioxothiazoli...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334177(2-(5-(3-methoxybenzylidene)-2,4-dioxothiazolidin-3...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334175(2-(2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334185(5-(3-(benzyloxy)benzylidene)-2-thioxothiazolidin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334184(5-(4-phenoxybenzylidene)-2-thioxothiazolidin-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50274894((Z)-5-(Naphthalen-1'-ylmethylene)-2-thioxothiazoli...)copy SMILEScopy InChI
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50202147(5-(3-phenoxybenzylidene)-2-thioxothiazolidin-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50247599((Z)-5-(4'-Hydroxybenzylidene)-2-thioxothiazolidin-...)copy SMILEScopy InChI
Affinity DataIC50: 4.55E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50241157((Z)-5-(4'-Methoxybenzylidene)-2-thioxothiazolidin-...)copy SMILEScopy InChI
Affinity DataIC50: 5.23E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334178(5-(3-phenoxybenzylidene)thiazolidine-2,4-dione | C...)copy SMILEScopy InChI
Affinity DataIC50: 6.14E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50241489((Z)-5-(3'-Methoxybenzylidene)-2-thioxothiazolidin-...)copy SMILEScopy InChI
Affinity DataIC50: 6.24E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM60579((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...)copy SMILEScopy InChI
Affinity DataIC50: 8.96E+3nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50334179(5-(naphthalen-1-ylmethylene)thiazolidine-2,4-dione...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM26634((5Z)-5-[(3-methoxyphenyl)methylidene]-1,3-thiazoli...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM26632((5Z)-5-[(4-methoxyphenyl)methylidene]-1,3-thiazoli...)copy SMILEScopy InChI
Affinity DataIC50: 4.08E+4nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP46C4PubMed