Compile Data Set for Download or QSAR
Found 42 Enz. Inhib. hit(s) with all data for entry = 50032872
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335958(2-(2'-(((benzyloxycarbonyl)(ethyl)amino)methyl)-4'...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change after 4 hrs by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human CYP3A4 by time-dependent inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335957(2-(2'-(((benzyloxycarbonyl)(ethyl)amino)methyl)-4'...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335951(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335959(2-(2'-(((benzyloxycarbonyl)(ethyl)amino)methyl)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335956(2-(4'-acetamido-2'-(((benzyloxycarbonyl)(ethyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335959(2-(2'-(((benzyloxycarbonyl)(ethyl)amino)methyl)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335952(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335961(2-(((benzyloxycarbonyl)(ethyl)amino)methyl)-5'-(ca...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335953(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-4'-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335958(2-(2'-(((benzyloxycarbonyl)(ethyl)amino)methyl)-4'...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335960(2-(2'-(((benzyloxycarbonyl)(ethyl)amino)methyl)-4'...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335952(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335955(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335953(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-4'-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape change by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335960(2-(2'-(((benzyloxycarbonyl)(ethyl)amino)methyl)-4'...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335955(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335951(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335951(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335952(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335953(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-4'-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335956(2-(4'-acetamido-2'-(((benzyloxycarbonyl)(ethyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335957(2-(2'-(((benzyloxycarbonyl)(ethyl)amino)methyl)-4'...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335955(2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-m...)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335961(2-(((benzyloxycarbonyl)(ethyl)amino)methyl)-5'-(ca...)copy SMILEScopy InChI
Affinity DataIC50: 254nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by liquid scintillation counting in presence of 0.2 % HSAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.67E+4nMAssay Description:Displacement of [3H]PGD2 from DP1 in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstacyclin receptor(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]iloprost from IP receptor in human 293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]SQ-29548 from TP receptor in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of PPAR alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of PPAR gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
USA.

Curated by ChEMBL
LigandPNGBDBM50335954(CHEMBL1668898 | Sodium [2'-[(cyclopropanecarbonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of PPAR betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZNTPubMed