Compile Data Set for Download or QSAR
Found 83 Enz. Inhib. hit(s) with all data for entry = 50032905
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 0.490nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant MEK1 expressed in insect cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant VEGFR1 expressed in Sf9 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336459((S,5E,11E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant PDGFRbeta expressed in insect cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336462((3S,5R,E)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336461((S,E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,1...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336461((S,E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,1...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336459((S,5E,11E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336461((S,E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,1...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50335376((S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50335376((S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336461((S,E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,1...)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50335376((S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336459((S,5E,11E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50335376((S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336466((3S,5R,E)-5-chloro-16-hydroxy-14-methoxy-3-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant ERK2 expressed in E.coli after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336459((S,5E,11E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336461((S,E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,1...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336465((3S,5R)-5-chloro-16-hydroxy-14-methoxy-3-methyl-3,...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336459((S,5E,11E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant ERK1 expressed in E.coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336457((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant GSK3alpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336458((3S,5R)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3,4...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336458((3S,5R)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3,4...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336462((3S,5R,E)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336462((3S,5R,E)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50335376((S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336458((3S,5R)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3,4...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336462((3S,5R,E)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336458((3S,5R)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3,4...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336463((3S,5R,Z)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336463((3S,5R,Z)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336459((S,5E,11E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10...)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human recombinant PDGFRbeta expressed in insect cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336458((3S,5R)-5-bromo-16-hydroxy-14-methoxy-3-methyl-3,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336461((S,E)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,1...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant MEK1 expressed in insect cells after 20 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336464((3S,5R,Z)-5-chloro-16-hydroxy-14-methoxy-3-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336464((3S,5R,Z)-5-chloro-16-hydroxy-14-methoxy-3-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant VEGFR1 expressed in Sf9 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336465((3S,5R)-5-chloro-16-hydroxy-14-methoxy-3-methyl-3,...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9HH5PubMed
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